common ancestor;
age estimation;
coalescent approach;
Y chromosome;
Alu sequence;
D O I:
10.1093/oxfordjournals.molbev.a025753
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
We present a simple Monte Carlo method for estimating the age of the most recent common ancestor (MRCA) of a sample of DNA sequences. We show that Templeton's (1993) estimator of the age of the MRCA based on the maximum number of nucleotide differences between two sequences in a sample is inaccurate, and we demonstrate the new method by reanalyzing a sample of DNA sequences from human Y chromosomes and a sample of human Alu sequences.
机构:
Univ Georgia, Plant Genome Mapping Lab, Athens, GA 30602 USA
Hebei United Univ, Ctr Genom & Computat Biol, Tangshan, Peoples R China
Hebei United Univ, Coll Life Sci, Tangshan, Peoples R ChinaUniv Georgia, Plant Genome Mapping Lab, Athens, GA 30602 USA
Wang, Xiyin
Guo, Hui
论文数: 0引用数: 0
h-index: 0
机构:
Univ Georgia, Plant Genome Mapping Lab, Athens, GA 30602 USA
Univ Georgia, Dept Plant Pathol, Athens, GA 30602 USAUniv Georgia, Plant Genome Mapping Lab, Athens, GA 30602 USA
Guo, Hui
Wang, Jingpeng
论文数: 0引用数: 0
h-index: 0
机构:
Hebei United Univ, Ctr Genom & Computat Biol, Tangshan, Peoples R China
Hebei United Univ, Coll Life Sci, Tangshan, Peoples R ChinaUniv Georgia, Plant Genome Mapping Lab, Athens, GA 30602 USA
Wang, Jingpeng
GENOMES OF HERBACEOUS LAND PLANTS,
2014,
69
: 175
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194