This is the first report of the efficacy of leukocytapheresis (LCAP) in a patient with refractory adult onset Still's disease (AOSD) during pregnancy. A 32-year-old Chinese pregnant woman with AOSD who had been treated with prednisolone failed to achieve disease stabilization. The patient's disease was successfully controlled with the initiation of LCAP. Subsequently, she gave birth via Caesarean section to a 1,878 g baby boy at 34 weeks of gestation while maintaining remission. We conclude that LCAP is an alternative treatment in pregnant patients with refractory AOSD, particularly in those concerned about potential teratogenic and other adverse effects.
机构:
Univ Ferrara, Dipartimento Med Clin & Sperimentale, Sez Reumatol, Azienda St Anna, I-44100 Ferrara, ItalyUniv Ferrara, Dipartimento Med Clin & Sperimentale, Sez Reumatol, Azienda St Anna, I-44100 Ferrara, Italy
Bagnari, Valentina
Colina, Matteo
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Univ Ferrara, Dipartimento Med Clin & Sperimentale, Sez Reumatol, Azienda St Anna, I-44100 Ferrara, ItalyUniv Ferrara, Dipartimento Med Clin & Sperimentale, Sez Reumatol, Azienda St Anna, I-44100 Ferrara, Italy
Colina, Matteo
Ciancio, Giovanni
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Univ Ferrara, Dipartimento Med Clin & Sperimentale, Sez Reumatol, Azienda St Anna, I-44100 Ferrara, ItalyUniv Ferrara, Dipartimento Med Clin & Sperimentale, Sez Reumatol, Azienda St Anna, I-44100 Ferrara, Italy
Ciancio, Giovanni
Govoni, Marcello
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Univ Ferrara, Dipartimento Med Clin & Sperimentale, Sez Reumatol, Azienda St Anna, I-44100 Ferrara, ItalyUniv Ferrara, Dipartimento Med Clin & Sperimentale, Sez Reumatol, Azienda St Anna, I-44100 Ferrara, Italy
机构:
Szent Laszlo Hosp Budapest, Favarosi Szent Laszlo Korhaz, Dept Internal Med 6, H-1097 Budapest, HungarySzent Laszlo Hosp Budapest, Favarosi Szent Laszlo Korhaz, Dept Internal Med 6, H-1097 Budapest, Hungary
Kádár, J
Petrovicz, E
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Szent Laszlo Hosp Budapest, Favarosi Szent Laszlo Korhaz, Dept Internal Med 6, H-1097 Budapest, HungarySzent Laszlo Hosp Budapest, Favarosi Szent Laszlo Korhaz, Dept Internal Med 6, H-1097 Budapest, Hungary
Petrovicz, E
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY,
2004,
18
(05):
: 663
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676
机构:
Univ Oklahoma, Hlth Sci Ctr, Dept Med, Oklahoma City, OK 73104 USAUniv Oklahoma, Hlth Sci Ctr, Dept Med, Oklahoma City, OK 73104 USA
Thanou-Stavraki, Aikaterini
Aberle, Teresa
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Univ Oklahoma, Hlth Sci Ctr, Dept Med, Oklahoma City, OK 73104 USAUniv Oklahoma, Hlth Sci Ctr, Dept Med, Oklahoma City, OK 73104 USA
Aberle, Teresa
Aksentijevich, Ivona
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机构:
NHGRI, Inflammatory Dis Sect, Bethesda, MD 20892 USAUniv Oklahoma, Hlth Sci Ctr, Dept Med, Oklahoma City, OK 73104 USA
Aksentijevich, Ivona
Bane, Barbara L.
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机构:
Univ Oklahoma, Hlth Sci Ctr, Dept Pathol, Oklahoma City, OK 73104 USAUniv Oklahoma, Hlth Sci Ctr, Dept Med, Oklahoma City, OK 73104 USA
Bane, Barbara L.
Harley, John B.
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机构:
Cincinnati Childrens Hosp Med Ctr, Div Rheumatol, Cincinnati, OH USA
Cincinnati Childrens Hosp Med Ctr, Autoimmune Genom Ctr, Cincinnati, OH USA
US Dept Vet Affairs Med Ctr, Cincinnati, OH USAUniv Oklahoma, Hlth Sci Ctr, Dept Med, Oklahoma City, OK 73104 USA