Resveratrol as an anti-cancer agent: A review

被引:480
|
作者
Rauf, Abdur [1 ]
Imran, Muhammad [2 ]
Butt, Masood Sadiq [3 ]
Nadeem, Muhammad [4 ]
Peters, Dennis G. [5 ]
Mubarak, Mohammad S. [6 ]
机构
[1] Univ Swabi, Dept Chem, Khyber Pakhtunkhwa, Pakistan
[2] Imperial Coll Business Studies, Dept Diet & Nutr Sci, Lahore, Pakistan
[3] Agr Univ Faisalabad, Fac Food Nutr & Home Sci, Faisalabad, Pakistan
[4] COMSATS Inst Informat Technol, Dept Environm Sci, Vehari 61100, Pakistan
[5] Indiana Univ, Dept Chem, Bloomington, IN USA
[6] Univ Jordan, Dept Chem, Amman 11942, Jordan
关键词
Resveratrol; chemopreventive agent; human cancers; APOPTOTIC CELL-DEATH; BLADDER-CANCER CELLS; TO-MESENCHYMAL TRANSITION; BREAST EPITHELIAL-CELLS; COLORECTAL-CANCER; DOWN-REGULATION; CYCLE ARREST; IN-VITRO; ESOPHAGEAL ADENOCARCINOMA; MITOCHONDRIAL DYSFUNCTION;
D O I
10.1080/10408398.2016.1263597
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Owing to their antimicrobial, antioxidant, and anti-inflammatory activity, grapes (Vitis vinifera L.) are the archetypal paradigms of fruits used not only for nutritional purposes, but also for exclusive therapeutics. Grapes are a prominent and promising source of phytochemicals, especially resveratrol, a phytoalexin antioxidant found in red grapes which has both chemopreventive and therapeutic effects against various ailments. Resveratrol's role in reducing different human cancers, including breast, cervical, uterine, blood, kidney, liver, eye, bladder, thyroid, esophageal, prostate, brain, lung, skin, gastric, colon, head and neck, bone, ovarian, and cervical, has been reviewed. This review covers the literature that deals with the anti-cancer mechanism of resveratrol with special reference to antioxidant potential. Furthermore, this article summarizes the literature pertaining to resveratrol as an anti-cancer agent.
引用
收藏
页码:1428 / 1447
页数:20
相关论文
共 50 条
  • [1] Anti-cancer perspectives of resveratrol: a comprehensive review
    Anwar, Muhammad Junaid
    Altaf, Areeba
    Imran, Muhammad
    Amir, Muhammad
    Alsagaby, Suliman A.
    Abdulmonem, Waleed Al
    Mujtaba, Ahmed
    El-Ghorab, Ahmed H.
    Ghoneim, Mohammed M.
    Hussain, Muzzamal
    Jbawi, Entessar Al
    Shaker, Mohamed E.
    Abdelgawad, Mohamed A.
    [J]. FOOD AND AGRICULTURAL IMMUNOLOGY, 2023, 34 (01)
  • [2] ANTI-CANCER AGENT
    ROBINSON, AB
    [J]. QUICK FROZEN FOODS, 1977, 40 (03): : 42 - 42
  • [3] A NEW ANTI-CANCER AGENT
    不详
    [J]. BMJ-BRITISH MEDICAL JOURNAL, 1962, (5271): : 104 - +
  • [4] Thalidomide as an anti-cancer agent
    Kumar, S
    Witzig, TE
    Rajkumar, SV
    [J]. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2002, 6 (02) : 160 - 174
  • [5] INTERFERON - ANTI-CANCER AGENT
    PRIESTMAN, TJ
    [J]. CANCER TREATMENT REVIEWS, 1979, 6 (04) : 223 - 237
  • [6] Resveratrol: An overview of its anti-cancer mechanisms
    Elshaer, Mohamed
    Chen, Yeru
    Wang, Xiu Jun
    Tang, Xiuwen
    [J]. LIFE SCIENCES, 2018, 207 : 340 - 349
  • [7] Piperine as a Potential Anti-cancer Agent: A Review on Preclinical Studies
    Manayi, Azadeh
    Nabavi, Seyed Mohammad
    Setzer, William N.
    Jafari, Samineh
    [J]. CURRENT MEDICINAL CHEMISTRY, 2018, 25 (37) : 4918 - 4928
  • [8] Doxycycline as Potential Anti-cancer Agent
    Ali, Isra
    Alfarouk, Khalid O.
    Reshkin, Stephan J.
    Ibrahim, Muntaser E.
    [J]. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2017, 17 (12) : 1617 - 1623
  • [9] Repurposing Disulfiram as An Anti-Cancer Agent: Updated Review on Literature and Patents
    Ekinci, Elmira
    Rohondia, Sagar
    Khan, Raheel
    Dou, Qingping P.
    [J]. RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2019, 14 (02) : 113 - 132
  • [10] The Evolving Roles of Bacopa monnieri as Potential Anti-Cancer Agent: A Review
    Ghosh, Sudeepa
    Khanam, Rahmat
    Acharya Chowdhury, Avik
    [J]. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 2021, 73 (11-12): : 2166 - 2176