Zinc-Catalyzed Cyclopropenation of Alkynes via 2-Furylcarbenoids

被引：50
|
作者：
Gonzalez, Maria J.
Lopez, Luis A. [1 ]
Vicente, Ruben
机构：
[1] Univ Oviedo, Dept Quim Organ & Inorgan, E-33006 Oviedo, Spain
来源：
ORGANIC LETTERS | 2014年 / 16卷 / 21期
关键词：
SOLID-STATE STRUCTURE; TERMINAL ALKYNES; CYCLOPROPANATION; INSERTION; FURAN; GENERATION; IZNCH2I;
D O I：
10.1021/ol502848n
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An unprecedented cyclopropenation reaction of alkynes catalyzed by ZnCl2 is reported. While SimmonsSmith-type carbenoids failed in the [2 + 1]-cycloaddition with alkynes, the use of enynones as the carbene source enables the preparation of substituted 2-furyl cyclopropene derivatives with remarkable scope.
引用
收藏
页码：5780 / 5783
页数：4
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