Preparation and characterization of the inclusion complex of Baicalin (BG) with β-CD and HP-β-CD in solution: An antioxidant ability study

被引：35
|
作者：
Li, Jinxia [1 ,2 ]
Zhang, Min [1 ]
Chao, Jianbin [1 ]
Shuang, Shaomin [2 ]
机构：
[1] Shanxi Univ, Inst Appl Chem, Taiyuan 030006, Peoples R China
[2] Shanxi Univ, Coll Chem & Chem Engn, Taiyuan 030006, Peoples R China
来源：
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2009年 / 73卷 / 04期
关键词：
Baicalin; Cyclodextrins; Absorption spectroscopy; Fluorescence; NMR; DPPH center dot; SCUTELLARIA-BAICALENSIS-GEORGI; CYCLODEXTRIN; STRESS;
D O I：
10.1016/j.saa.2009.03.025
中图分类号：
O433 [光谱学];
学科分类号：
0703 ; 070302 ;
摘要：
The formation of the complexes of BG with beta-CD and HP-beta-CD was studied by UV-vis absorption spectroscopy, fluorescence spectra, Phase-solubility measurements and nuclear magnetic resonance spectroscopy (NMR) in solution. The formation constants (K) of complexes were determined by fluorescence method and Phase-solubility measurements. The results showed that the inclusion ability of beta-CD and its derivatives was the order: HP-beta-CD > beta-CD. In addition, the experimental resulted confirmed the existence of 1:1 inclusion complex of BG with CDs. The antioxidant ability studies of BG and CDs complexes were done. The results obtained indicated that the BG/HP-beta-CD complex was the most reactive form, and then was the BG/beta-CD complex; the last was BG. Special configuration of complex has been proposed on NMR technique. (C) 2009 Elsevier B.V. All rights reserved.
引用
收藏
页码：752 / 756
页数：5
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