Recent developments in the synthesis of zoanthamine alkaloids

被引：6
|
作者：
Yoshimura, Fumihiko [1 ]
Tanino, Keiji [1 ]
Miyashita, Masaaki [1 ]
机构：
[1] Hokkaido Univ, Fac Sci, Dept Chem, Sapporo, Hokkaido 0600810, Japan
来源：
TETRAHEDRON LETTERS | 2014年 / 55卷 / 18期
关键词：
Zoanthamine alkaloids; Total synthesis; Quaternary asymmetric carbon atom; Aminoacetal; MICHAEL REACTION CASCADE; ABC-RING; MARINE ZOANTHID; ENANTIOSELECTIVE SYNTHESIS; ASYMMETRIC-SYNTHESIS; ORGANIC-SYNTHESIS; CARBOCYCLIC CORE; NORZOANTHAMINE; CYCLIZATION; CONSTRUCTION;
D O I：
10.1016/j.tetlet.2014.03.073
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
This review provides a compilation of the most recent synthetic approaches and total syntheses of zoanthamine alkaloids, which are structurally unique heptacyclic marine natural products that display a range of interesting biological activities. This review is focused on synthetic methodologies for the construction of the three adjacent quaternary asymmetric carbon atoms on the cyclohexane ring (C-ring) of these compounds. The literature covered in this review dates from 2008 to the end of 2013. (C) 2014 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-SA license
引用
收藏
页码：2895 / 2903
页数：9
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