Development of a fluorescent sensor for illicit date rape drug GHB

被引：32
|
作者：
Zhai, Duanting [1 ,2 ]
Tan, Yong Qiao Elton [1 ,2 ]
Xu, Wang [1 ,2 ]
Chang, Young-Tae [1 ,2 ,3 ]
机构：
[1] Natl Univ Singapore, Dept Chem, Singapore 117543, Singapore
[2] Natl Univ Singapore, Inst Life Sci, MedChem Program, Singapore 117543, Singapore
[3] ASTAR, Singapore Bioimaging Consortium SBIC, Lab Bioimaging Probe Dev, Singapore 138667, Singapore
来源：
CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 22期
关键词：
GAMMA-HYDROXYBUTYRATE; BEVERAGES; PROBE; GBL;
D O I：
10.1039/c3cc49603a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The first fluorescent sensor (GHB Orange) for date rape drug GHB was developed. It exhibits the fluorescence quenching property for GHB and allows its detection in various drinks. The interaction mechanism was elucidated as intramolecular charge transfer induced by a hydrogen bond. This discovery will help in solving the drug facilitated sexual assault problems.
引用
收藏
页码：2904 / 2906
页数：3
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