The NIH Common Fund/Roadmap Epigenomics Program: Successes of a comprehensive consortium

被引：29
|
作者：
Satterlee, John S. [1 ,2 ]
Chadwick, Lisa H. [2 ,6 ]
Tyson, Frederick L. [3 ]
McAllister, Kim [3 ]
Beaver, Jill [4 ,5 ]
Birnbaum, Linda [3 ]
Volkow, Nora D. [2 ]
Wilder, Elizabeth L. [4 ,5 ]
Anderson, James M. [4 ]
Roy, Ananda L. [4 ,5 ]
机构：
[1] NIH, Div Neurosci & Behav, 6001 Execut Blvd, Bethesda, MD 20892 USA
[2] NIDA, NIH, 6001 Execut Blvd, Bethesda, MD 20892 USA
[3] NIEHS, NIH, 111 TW Alexander Dr, Durham, NC 27709 USA
[4] NIH, Off Strateg Coordinat, Off Director, 6001 Execut Blvd, Bethesda, MD 20892 USA
[5] NIH, Div Program Coordinat Planning & Strateg Initiati, Off Director, 6001 Execut Blvd, Bethesda, MD 20892 USA
[6] NHGRI, Div Genome Sci, NIH, 6001 Execut Blvd, Bethesda, MD 20892 USA
来源：
SCIENCE ADVANCES | 2019年 / 5卷 / 07期
关键词：
DNA METHYLATION; ROADMAP;
D O I：
10.1126/sciadv.aaw6507
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The NIH Roadmap Epigenomics Program was launched to deliver reference epigenomic data from human tissues and cells, develop tools and methods for analyzing the epigenome, discover novel epigenetic marks, develop methods to manipulate the epigenome, and determine epigenetic contributions to diverse human diseases. Here, we comment on the outcomes from this program: the scientific contributions made possible by a consortium approach and the challenges, benefits, and lessons learned from this group science effort.
引用
收藏
页数：6
相关论文
共 50 条
  • [1] The NIH Roadmap Epigenomics Mapping Consortium
    Bradley E Bernstein
    John A Stamatoyannopoulos
    Joseph F Costello
    Bing Ren
    Aleksandar Milosavljevic
    Alexander Meissner
    Manolis Kellis
    Marco A Marra
    Arthur L Beaudet
    Joseph R Ecker
    Peggy J Farnham
    Martin Hirst
    Eric S Lander
    Tarjei S Mikkelsen
    James A Thomson
    [J]. Nature Biotechnology, 2010, 28 : 1045 - 1048
  • [2] The NIH Roadmap Epigenomics Mapping Consortium
    Bernstein, Bradley E.
    Stamatoyannopoulos, John A.
    Costello, Joseph F.
    Ren, Bing
    Milosavljevic, Aleksandar
    Meissner, Alexander
    Kellis, Manolis
    Marra, Marco A.
    Beaudet, Arthur L.
    Ecker, Joseph R.
    Farnham, Peggy J.
    Hirst, Martin
    Lander, Eric S.
    Mikkelsen, Tarjei S.
    Thomson, James A.
    [J]. NATURE BIOTECHNOLOGY, 2010, 28 (10) : 1045 - 1048
  • [3] The NIH Roadmap Epigenomics Program data resource
    Chadwick, Lisa Helbling
    [J]. EPIGENOMICS, 2012, 4 (03) : 317 - 324
  • [4] NIH Roadmap/Common Fund at 10 years
    Collins, Francis S.
    Wilder, Elizabeth L.
    Zerhouni, Elias
    [J]. SCIENCE, 2014, 345 (6194) : 274 - 276
  • [5] NIH Common Fund Explanation of the Molecular Transducers of Physical Activity Consortium
    Williams, John P.
    Miller, Craig B.
    [J]. GERONTOLOGIST, 2015, 55
  • [6] The NIH Common Fund's Extracellular RNA (exRNA) Communication Program.
    Kuo, L.
    [J]. MOLECULAR BIOLOGY OF THE CELL, 2017, 28
  • [7] THE NIH SCIENCE OF BEHAVIOR CHANGE COMMON FUND PROGRAM: WHY, WHAT, AND WHEN?
    King, Jonathan W.
    [J]. ANNALS OF BEHAVIORAL MEDICINE, 2020, 54 : S463 - S463
  • [8] THE NIH SCIENCE OF BEHAVIOR CHANGE (SOBC) COMMON FUND PROGRAM: RATIONALE AND GOALS
    Hunter, Christine M.
    [J]. ANNALS OF BEHAVIORAL MEDICINE, 2017, 51 : S1595 - S1595
  • [9] New NIH Common Fund Programs
    不详
    [J]. JOURNAL OF NUCLEAR MEDICINE, 2010, 51 (04) : 20N - 21N
  • [10] NIH Common Fund Initiatives Announced
    不详
    [J]. JOURNAL OF INVESTIGATIVE MEDICINE, 2010, 58 (05) : 696 - 696
12345