The NIH Roadmap Epigenomics Mapping Consortium

被引：1247

作者：

Bernstein, Bradley E. ^{[1
,2
,3
]}

Stamatoyannopoulos, John A. ^{[5
,6
]}

Costello, Joseph F. ^{[7
]}

Ren, Bing ^{[8
]}

Milosavljevic, Aleksandar ^{[9
]}

Meissner, Alexander ^{[1
,4
]}

Kellis, Manolis ^{[1
]}

Marra, Marco A. ^{[10
]}

Beaudet, Arthur L. ^{[9
]}

Ecker, Joseph R. ^{[11
]}

Farnham, Peggy J. ^{[12
]}

Hirst, Martin ^{[10
]}

Lander, Eric S. ^{[1
]}

Mikkelsen, Tarjei S. ^{[1
]}

Thomson, James A. ^{[13
]}

机构：

[1] Harvard & MIT, Broad Inst, Cambridge, MA USA

[2] Massachusetts Gen Hosp, Dept Pathol, Howard Hughes Med Inst, Boston, MA 02114 USA

[3] Harvard Univ, Sch Med, Boston, MA USA

[4] Harvard Univ, Dept Stem Cell & Regenerat Biol, Cambridge, MA 02138 USA

[5] Univ Washington, Sch Med, Dept Genome Sci, Seattle, WA USA

[6] Univ Washington, Sch Med, Dept Med, Seattle, WA 98195 USA

[7] Univ Calif San Francisco, Dept Neurosurg, San Francisco, CA 94143 USA

[8] Univ Calif San Diego, Sch Med, Ludwig Inst Canc Res, La Jolla, CA 92093 USA

[9] Baylor Coll Med, Dept Mol & Human Genet, Houston, TX 77030 USA

[10] British Columbia Canc Agcy, Genome Sci Ctr, Vancouver, BC V5Z 4E6, Canada

[11] Salk Inst Biol Studies, Genom Anal Lab, La Jolla, CA 92037 USA

[12] Univ Calif Davis, Genome Ctr, Davis, CA 95616 USA

[13] Univ Wisconsin, Sch Med & Publ Hlth, Madison, WI USA

来源：

NATURE BIOTECHNOLOGY | 2010年 / 28卷 / 10期

关键词：

GENE-EXPRESSION; EPIGENETIC REGULATION; HUMAN-DISEASE; HUMAN GENOME; PLURIPOTENT; MECHANISMS; CELLS; MAPS;

D O I：

10.1038/nbt1010-1045

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The NIH Roadmap Epigenomics Mapping Consortium aims to produce a public resource of epigenomic maps for stem cells and primary ex vivo tissues selected to represent the normal counterparts of tissues and organ systems frequently involved in human disease.

引用

页码：1045 / 1048

页数：4

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Manolis Kellis
Marco A Marra
Arthur L Beaudet
Joseph R Ecker
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Martin Hirst
Eric S Lander
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