Alliacane sesquiterpenoids from submerged cultures of the basidiomycete Inonotus sp BCC 22670

被引：7

作者：

Isaka, Masahiko ^{[1
]}

Sappan, Malipan ^{[1
]}

Supothina, Sumalee ^{[1
]}

Srichomthong, Kitlada ^{[1
]}

Komwijit, Somjit ^{[1
]}

Boonpratuang, Thitiya ^{[1
]}

机构：

[1] Natl Ctr Genet Engn & Biotechnol BIOTEC, 113 Thailand Sci Pk,Phaholyothin Rd, Klongluang 12120, Pathumthani, Thailand

来源：

PHYTOCHEMISTRY | 2017年 / 136卷

关键词：

Inonotus; Hymenochaetaceae; Alliacane; Antibacterial activity; Antiviral activity; METABOLITES; FUNGI;

D O I：

10.1016/j.phytochem.2017.01.018

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Nine alliacane sesquiterpenoids, inonoalliacanes A-I, were isolated from culture broth of the basidiomycete Inonotus sp. BCC 22670. The structures were elucidated on the basis of NMR spectroscopic and mass spectrometry data. The absolute configuration of inonoalliacane F was determined by application of the modified Mosher's method. Inonoalliacane A, the most abundant sesquiterpene constituent, exhibited moderate antibacterial activity against Bacillus cereus, whereas inonoalliacane B showed antiviral activity against herpes simplex virus type 1. (C) 2017 Elsevier Ltd. All rights reserved.

引用

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页码：175 / 181

页数：7

共 36 条

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