Palladium-catalyzed direct alkynylation of thiophenes with halosilylacetylenes

被引：2
|
作者：
Kato, Hayate [1 ]
Tsukada, Naofumi [1 ]
机构：
[1] Shizuoka Univ, Fac Sci, Dept Chem, Suruga Ku, 836 Ohya, Shizuoka 4228529, Japan
来源：
TETRAHEDRON LETTERS | 2021年 / 67卷
关键词：
Palladium; Thiophene; Alkyne; Regioselective reaction; C-H functionalization; H BOND ARYLATION; COUPLING REACTIONS; TERMINAL ALKYNES; HETEROCYCLES; ACTIVATION; INDOLES; ACCESS; ACIDS; ARYL;
D O I：
10.1016/j.tetlet.2021.152869
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Silylethynylthiophenes were obtained from palladium-catalyzed alkynylation of various thiophenes with 1-halo-2-silylacetylenes. The a-position of thiophenes was alkynylated with high regioselectivity. The terminal silyl groups of products could be replaced by several functional groups. (C) 2021 Elsevier Ltd. All rights reserved.
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页数：3
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