Measuring human beta-secretase (BACE1) activity using homogeneous time-resolved fluorescence

被引：0
|
作者：
Kennedy, M
Song, LX
Lee, J
Zhang, LL
Wong, G
Wang, LY
Parker, E
Beyer, B
Wang, WY
机构：
[1] Schering Plough Corp, Res Inst, CV Res, CNS, Kenilworth, NJ 07033 USA
[2] Schering Plough Corp, Res Inst, Struct Chem, Kenilworth, NJ 07033 USA
来源：
NEUROBIOLOGY OF AGING | 2002年 / 23卷 / 01期
关键词：
D O I：
暂无
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
689
引用
收藏
页码：S184 / S184
页数：1
相关论文
共 50 条
  • [31] Exploring 2D-QSAR for prediction of beta-secretase 1 (BACE1) inhibitory activity against Alzheimer's disease
    Kumar, V
    Ojha, P. K.
    Saha, A.
    Roy, K.
    SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 2020, 31 (02) : 87 - 133
  • [32] Simple Structure-Based Approach for Predicting the Activity of Inhibitors of Beta-Secretase (BACE1) Associated with Alzheimer's Disease
    Nastase, Anthony F.
    Boyd, Donald B.
    JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2012, 52 (12) : 3302 - 3307
  • [33] COMP 344-Molecular modeling, synthesis and activity studies of inhibitors targeting Alzheimer's disease beta-secretase (BACE1)
    Pachaiyappan, Boobalan
    Chirapu, Srinivasa Reddy
    Zhong, Zhenyu
    Yuan, Hongbin
    Abdul-Hay, Samer O.
    Thatcher, Gregory R. J.
    Kozikowski, Alan
    Shen, Yong
    Petukhov, Pavel A.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2008, 236
  • [34] Post-translational modifications of beta-secretase (BACE1) sorting signal regulates endosomal trafficking and amyloid beta production
    Toh, W.
    Chia, P. C.
    Gleeson, P. A.
    MOLECULAR BIOLOGY OF THE CELL, 2015, 26
  • [35] Beta-secretase for the production of beta-amyloid peptide in the regulated secretory pathway of neuronal chromaffin cells: Cysteine proteases in combination with BACE 1 for beta-secretase activity
    Hook, V
    Toneff, T
    Reisine, T
    NEUROBIOLOGY OF AGING, 2002, 23 (01) : S177 - S177
  • [36] A homogeneous time-resolved fluorescence detection of telomerase activity
    Gabourdes, M
    Bourgine, V
    Mathis, G
    Bazin, H
    Alpha-Bazin, W
    ANALYTICAL BIOCHEMISTRY, 2004, 333 (01) : 105 - 113
  • [37] A simple and rapid assay for heparanase activity using homogeneous time-resolved fluorescence
    Enomoto, K
    Okamoto, H
    Numata, Y
    Takemoto, H
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2006, 41 (03) : 912 - 917
  • [38] Lack of evidence to support the association of polymorphisms within the alpha- and beta-secretase genes (ADAM10/BACE1)
    Laws, S. M.
    Eckart, K.
    Friedrich, P.
    Kurz, A.
    Foerstl, H.
    Riemenschneider, M.
    NEUROBIOLOGY OF AGING, 2011, 32 (03) : 541 - 543
  • [39] Discovery of a series of selective and cell permeable beta-secretase (BACE1) inhibitors by fragment linking with the assistance of STD-NMR
    Fang, Wei-Shuo
    Sun, De-yang
    Yang, Shuang
    Cheng, Chen
    Moschke, Katrin
    Li, Tianqi
    Sun, Shanshan
    Lichtenthaler, Stefan F.
    Huang, Jian
    Wang, Yinghong
    BIOORGANIC CHEMISTRY, 2019, 92
  • [40] 2D QSAR Studies on Series of Human Beta-secretase (BACE-1) Inhibitors
    Cruz, Daniela Santos
    Castilho, Marcelo Santos
    MEDICINAL CHEMISTRY, 2014, 10 (02) : 162 - 173
12345