Implementation of Zebrafish Toxicity Testing Between In Vitro and In Vivo Models to Advance Candidate Selection

被引:0
|
作者
Hill, Adrian [1 ]
Ball, Jonathan [1 ]
Jones, Mathew [1 ]
Dodd, Andrew [1 ]
机构
[1] Summit Plc, Abingdon OX14 4RY, Oxon, England
关键词
Zebrafish; Toxicity testing; Candidate selection;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
P5
引用
收藏
页码:44 / 45
页数:2
相关论文
共 50 条
  • [41] Closing the gap between cell death and in vitro toxicity testing
    Zucco, F
    ANIMAL ALTERNATIVES, WELFARE, AND ETHICS, 1997, 27 : 541 - 548
  • [42] In vitro cytotoxicity and in vivo zebrafish toxicity evaluation of Ru(ii)/2-mercaptopyrimidine complexes
    Velozo-Sa, Vivianne S.
    Pereira, Luciano R.
    Lima, Aliny P.
    Mello-Andrade, Francyelli
    Rezende, Manuela R. M.
    Goveia, Rebeca M.
    Pires, Wanessa C.
    Silva, Monize M.
    Oliveira, Katia M.
    Ferreira, Antonio G.
    Ellena, Javier
    Deflon, Victor M.
    Grisolia, Cesar Koppe
    Batista, Alzir A.
    Silveira-Lacerda, Elisangela P.
    DALTON TRANSACTIONS, 2019, 48 (18) : 6026 - 6039
  • [43] In vitro models of human development and their potential application in developmental toxicity testing
    Niethammer, Mirjam
    Burgdorf, Tanja
    Wistorf, Elisa
    Schoenfelder, Gilbert
    Kleinsorge, Mandy
    DEVELOPMENT, 2022, 149 (20):
  • [44] Authenticated lung and gingival fibroblasts cell models for in vitro toxicity testing
    Sanchez, G.
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2020, 393 (SUPPL 1) : 85 - 85
  • [45] Bridging the gap between in vitro and in vivo models for neurotoxicology
    Tiffany-Castiglioni, E
    Ehrich, M
    Dees, L
    Costa, LG
    Kodavanti, PRS
    Lasley, SM
    Oortgiesen, M
    Durham, HD
    TOXICOLOGICAL SCIENCES, 1999, 51 (02) : 178 - 183
  • [46] Preliminary insight on diarylpentanoids as potential antimalarials: In silico, in vitro pLDH and in vivo zebrafish toxicity assessment
    Ramli, Amirah Hani
    Swain, Puspanjali
    Fahmi, Muhammad Syafiq Akmal Mohd
    Abas, Faridah
    Leong, Sze Wei
    Tejo, Bimo Ario
    Shaari, Khozirah
    Ali, Amatul Hamizah
    Agustar, Hani Kartini
    Awang, Rusdam
    Ng, Yee Ling
    Lau, Yee Ling
    Razali, Mohammad Aidiel Md
    Mastuki, Siti Nurulhuda
    Misnan, Norazlan Mohmad
    Faudzi, Siti Munirah Mohd
    Kim, Cheol-Hee
    HELIYON, 2024, 10 (05)
  • [47] Synergistic bone marrow toxicity of pyrimethamine and zidovudine in murine in vivo and in vitro models:: Mechanism of toxicity
    Freund, YR
    Dabbs, J
    Creek, MR
    Phillips, SJ
    Tyson, CA
    MacGregor, JT
    TOXICOLOGY AND APPLIED PHARMACOLOGY, 2002, 181 (01) : 16 - 26
  • [48] In vivo photogenotoxicity testing, bridging the gap between in vitro photogenotoxicity and photocarcinogenicity testing
    Krul, Cyrille
    Maas, Wilfred
    van Meeuwen, Richard
    de Vogel, Nico
    Steenwinkel, Marie Jose
    MUTAGENESIS, 2006, 21 (04) : 278 - 278
  • [49] In vivo photogenotoxicity testing, bridging the gap between in vitro photogenotoxicity and photocarcinogenicity testing
    Krul, Cyrille
    Maas, Wilfred
    van Meeuwen, Richard
    de Vogel, Nico
    Steenwinkel, Marie Jose
    TOXICOLOGY, 2006, 226 (01) : 27 - 27
  • [50] Developmental and organ-specific toxicity of cucurbit[7]uril: in vivo study on zebrafish models
    Chen, Huanxian
    Chan, Judy Y. W.
    Yang, Xue
    Wyman, Ian W.
    Bardelang, David
    Macartney, Donal H.
    Lee, Simon M. Y.
    Wang, Ruibing
    RSC ADVANCES, 2015, 5 (38): : 30067 - 30074