Glucose Biosensor Based on Nanocomposite Films of CdTe Quantum Dots and Glucose Oxidase

被引：160
|
作者：
Li, Xinyu [1 ]
Zhou, Yunlong [2 ]
Zheng, Zhaozhu [1 ]
Yue, Xiuli [3 ]
Dai, Zhifei [1 ]
Liu, Shaoqin [1 ,4 ]
Tang, Zhiyong [2 ]
机构：
[1] Harbin Inst Technol, Bio X Ctr, Nanomed & Biosensor Lab, Harbin 150080, Peoples R China
[2] Natl Ctr Nanosci & Technol, Beijing 100190, Peoples R China
[3] Harbin Inst Technol, Sch Municipal & Environm Engn, Harbin 150001, Peoples R China
[4] Harbin Inst Technol, Ctr Micro & Nanotechnol, Harbin 150080, Peoples R China
来源：
LANGMUIR | 2009年 / 25卷 / 11期
关键词：
CYTOCHROME-C; POLYELECTROLYTE; CDSE; NANOSTRUCTURES; NANOPARTICLES; PERMEABILITY; NANOCRYSTALS; OXIDATION; CHITOSAN; SYSTEMS;
D O I：
10.1021/la900066z
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A blood glucose sensor has been developed based on the multilayer films of CdTe semiconductor quantum dots (QDs) and glucose oxidase (GOD) by using the layer-by-layer assembly technique. When the composite films were contacted with glucose solution, the photoluminescence of QDs in the films was quickly quenched because the enzyme-catalyzed reaction product (H2O2) of GOD and glucose gave rise to the formation of surface defects on QDs. The quenching rate was a function of the concentration of glucose. The linear range and sensitivity for glucose determination could be adjusted by controlling the layers of QDs and GOD. The biosensor was used to successfully deter-mine the concentration of blood glucose in real serum samples without sample pretreatment and exhibited satisfactory reproducibility and accuracy.
引用
收藏
页码：6580 / 6586
页数：7
相关论文
共 50 条
  • [11] Construction of an Amperometric Glucose Biosensor by Immobilization of Glucose Oxidase on Nanocomposite at the Surface of FTO Electrode
    Marand, Zahra Rezay
    Shahtahmassebi, Nasser
    Housaindokht, Mohammad Reza
    Rounaghi, Golam Hossien
    Razavipanah, Iman
    ELECTROANALYSIS, 2014, 26 (04) : 840 - 848
  • [12] Amperometric glucose biosensor based on silver nanowires and glucose oxidase
    Wang, Lisha
    Gao, Xia
    Jin, Lingyan
    Wu, Qi
    Chen, Zhichun
    Lin, Xianfu
    SENSORS AND ACTUATORS B-CHEMICAL, 2013, 176 : 9 - 14
  • [13] Bioconjugation of concanavalin and CdTe quantum dots and the detection of glucose
    Wang, Jian-Hao
    Li, Yong-Qiang
    Zhang, Hai-Li
    Wang, Hai-Qiao
    Lin, Song
    Chen, Jun
    Zhao, Yuan-Di
    Luo, Qing-Ming
    COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2010, 364 (1-3) : 82 - 86
  • [14] A reagentless glucose biosensor based on glucose oxidase entrapped into osmium-complex modified polypyrrole films
    Reiter, S
    Habermüller, K
    Schuhmann, W
    SENSORS AND ACTUATORS B-CHEMICAL, 2001, 79 (2-3) : 150 - 156
  • [15] Conformation and activity dependent interaction of glucose oxidase with CdTe quantum dots: towards developing a nanoparticle based enzymatic assay
    Priyam, Amiya
    Chatterjee, Anindita
    Bhattacharya, Subhash C.
    Saha, Abhijit
    PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, 2009, 8 (03) : 362 - 370
  • [16] A Hybrid Enzyme Biosensor Based on Sulfite Oxidase and Glucose Oxidase for the Analyzing of Sulfite and Glucose
    Sezginturk, Mustafa Kemal
    Alacam, Sencer
    Altug, Cagri
    Akbayirli, Pinar
    Dinckaya, Erhan
    ANALYTICAL & BIOANALYTICAL ELECTROCHEMISTRY, 2012, 4 (02): : 153 - 162
  • [17] Biosensor composed of integrated glucose oxidase with liposome microreactors/chitosan nanocomposite for amperometric glucose sensing
    Guan Huanan
    Gong Dezhuang
    Song Yan
    Han Bolin
    Zhang Na
    COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2019, 574 : 260 - 267
  • [18] A Novel Glucose Biosensor at Glucose Oxidase Immobilized Graphene and Bismuth Nanocomposite Film Modified Electrode
    Mani, Veerappan
    Devasenathipathy, Rajkumar
    Chen, Shen-Ming
    Subramani, Boopathi
    Govindasamy, Mani
    INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE, 2015, 10 (01): : 691 - 700
  • [19] Whispering gallery mode resonator and glucose oxidase based glucose biosensor
    Brice, Inga
    Grundsteins, Karlis
    Atvars, Aigars
    Alnis, Janis
    Viter, Roman
    Ramanavicius, Arunas
    SENSORS AND ACTUATORS B-CHEMICAL, 2020, 318
  • [20] A glucose biosensor based on immobilization of glucose oxidase in chitosan network matrix
    Yao, H
    Li, N
    Xu, JZ
    Zhu, JJ
    CHINESE JOURNAL OF CHEMISTRY, 2005, 23 (03) : 275 - 279
12345