Tribromoisocyanuric acid: A new reagent for regioselective cobromination of alkenes

被引：85
|
作者：
de Almeida, Leonardo S. [1 ]
Esteves, Pierre M. [1 ]
de Mattos, Marcio C. S. [1 ]
机构：
[1] Univ Fed Rio de Janeiro, Dept Quim Organ, Inst Quim, BR-21945970 Rio De Janeiro, Brazil
来源：
SYNLETT | 2006年 / 10期
关键词：
alkenes; cohalogenation; Oxonel (R); tribromoisocyanuric acid;
D O I：
10.1055/s-2006-941601
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple one-step method for the preparation of tribromoisocyanuric acid in good yield (87%) has been developed. The reaction of tribromoisocyanuric acid with alkenes in presence of nucleophilic solvents (MeOH, i-PrOH, AcOH and a mixture of H2O-acetone, 1:5) led to the corresponding beta-bromoethers, beta-bromoacetates and bromohydrins, in high regioselectivity and good yields (73-98%).
引用
收藏
页码：1515 / 1518
页数：4
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