Isolation and structures of new azaphilone derivatives, falconensins E-G, from Emericella falconensis and absolute configurations of falconensins A-G

被引:0
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作者
Itabashi, T [1 ]
Ogasawara, N [1 ]
Nozawa, K [1 ]
Kawai, K [1 ]
机构
[1] HOSHI UNIV, FAC PHARMACEUT SCI, SHINAGAWA KU, TOKYO 142, JAPAN
关键词
Emericella falconensis; azaphilone; falconensin E; falconensin F; falconensin G; hopane-type triterpene;
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Three new azaphilone derivatives designated falconensins E (5), F (6), and G (7) were isolated from the mycelium of Emericella falconensis, along with falconensins A (1), B (2), C (3), D (4), and H (8), and three hopane-type triterpenes, zeorin (9), hopane-7 beta,22-diol (10), and hopane-6 alpha,7 beta,22-triol (11). The structures of 5-7 were confirmed by spectroscopic investigation and chemical correlations. The absolute stereochemistry of falconensins A (1) to G (7) was also established.
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页码:2213 / 2217
页数:5
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