Thyroid transcription factor-1 is a marker of lung and thyroid carcinomas

被引：186
|
作者：
Ordóñez, NG [1 ]
机构：
[1] Univ Texas, MD Anderson Canc Ctr, Houston, TX 77030 USA
来源：
ADVANCES IN ANATOMIC PATHOLOGY | 2000年 / 7卷 / 02期
关键词：
transcription factors; TTF-1; lung neoplasms; thyroid neoplasms; immunohistochemistry;
D O I：
10.1097/00125480-200007020-00007
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Thyroid transcription factor-1 (TTF-1) is a tissue specific transcription Factor expressed in epithelial cells of the thyroid and lung, as well as in certain areas of the brain. Recent investigations have shown that TTF-1 is also commonly present in a wide variety of thyroid and lung tumors. Because of its restrictive expression, TTF-1 is a useful immunohistochemical marker in the diagnosis of tumors of thyroid or lung origin.
引用
收藏
页码：123 / 127
页数：5
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