Candidate genes in women with polycystic ovary syndrome

被引:3
|
作者
Franks, Stephen [1 ]
机构
[1] Univ London Imperial Coll Sci & Technol, Hammersmith Hosp, Inst Reprod & Dev Biol, London W12 0NN, England
关键词
oligogenic; polygenic; follicle development; steroidogenesis; insulin action;
D O I
10.1016/j.fertnstert.2006.04.016
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
There is plentiful evidence that genetic factors have an important part to play in the etiology of polycystic ovary syndrome. As yet, however, none of the potential candidate loci have withstood the scrutiny of large case-control studies, although studies of a locus-close to the insulin receptor gene on chromosome 1.9p are emerging as promising.
引用
收藏
页码:S15 / S15
页数:1
相关论文
共 50 条
  • [1] Genetics and infertility II - Candidate genes in polycystic ovary syndrome
    Franks, S
    Gharani, N
    McCarthy, M
    HUMAN REPRODUCTION UPDATE, 2001, 7 (04) : 405 - 410
  • [2] Candidate genes for polycystic ovary syndrome are regulated by TGFβ in the bovine foetal ovary
    Azumah, Rafiatu
    Liu, Menghe
    Hummitzsch, Katja
    Bastian, Nicole A.
    Hartanti, Monica D.
    Irving-Rodgers, Helen F.
    Anderson, Richard A.
    Rodgers, Raymond J.
    HUMAN REPRODUCTION, 2022, 37 (06) : 1244 - 1254
  • [3] Family-Based Analysis of Candidate Genes for Polycystic Ovary Syndrome
    Ewens, Kathryn G.
    Stewart, Douglas R.
    Ankener, Wendy
    Urbanek, Margrit
    McAllister, Jan M.
    Chen, Chen
    Baig, K. Maravet
    Parker, Stephen C. J.
    Margulies, Elliot H.
    Legro, Richard S.
    Dunaif, Andrea
    Strauss, Jerome F., III
    Spielman, Richard S.
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2010, 95 (05): : 2306 - 2315
  • [4] Harnessing Expression Data to Identify Novel Candidate Genes in Polycystic Ovary Syndrome
    Jones, Michelle R.
    Chua, Angela
    Chen, Yii-Der I.
    Li, Xiaohui
    Krauss, Ronald M.
    Rotter, Jerome I.
    Legro, Richard S.
    Azziz, Ricardo
    Goodarzi, Mark O.
    PLOS ONE, 2011, 6 (05):
  • [5] IDENTIFICATION OF NOVEL MUTATIONS IN CANDIDATE GENES ASSOCIATED WITH POLYCYSTIC OVARY SYNDROME (PCOS) IN WOMEN WITH ARAB ETHNICITY.
    Al-Khaduri, Maha
    Al Kindi, Fatima Ahmed
    Tamimi, Yahya
    Nomani, Ammar Hamed
    Al-Farsi, Yahya M.
    FERTILITY AND STERILITY, 2020, 114 (03) : E542 - E543
  • [6] Identification of potential diagnostic genes for atherosclerosis in women with polycystic ovary syndrome
    Luo, Yujia
    Zhou, Yuanyuan
    Jiang, Hanyue
    Zhu, Qiongjun
    Lv, Qingbo
    Zhang, Xuandong
    Gu, Rui
    Yan, Bingqian
    Wei, Li
    Zhu, Yuhang
    Jiang, Zhou
    SCIENTIFIC REPORTS, 2024, 14 (01):
  • [7] POLYCYSTIC OVARY SYNDROME IN 2011 Genes, aging and sleep apnea in polycystic ovary syndrome
    Dunaif, Andrea
    NATURE REVIEWS ENDOCRINOLOGY, 2012, 8 (02) : 72 - 74
  • [8] An investigation of steroid biosynthesis pathway genes in women with polycystic ovary syndrome
    Sharma, Priyal
    Jain, Manish
    Halder, Ashutosh
    JOURNAL OF HUMAN REPRODUCTIVE SCIENCES, 2022, 15 (03) : 240 - 249
  • [9] Searching for the polycystic ovary syndrome genes
    Urbanek, M
    Legro, RS
    Driscoll, D
    Strauss, JF
    Dunaif, A
    Spielman, RS
    JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, 2000, 13 : 1311 - 1313
  • [10] Family-Based Analysis of Candidate Genes for Polycystic Ovary Syndrome EDITORIAL COMMENT
    Ewens, Kathryn G.
    Stewart, Douglas R.
    Ankener, Wendy
    Urbanek, Margrit
    McAllister, Jan M.
    Chen, Chen
    Baig, K. Maravet
    Parker, Stephen C. J.
    Margulies, Elliot H.
    Legro, Richard S.
    Dunaif, Andrea
    Strauss, Jerome F., III
    Spielman, Richard S.
    OBSTETRICAL & GYNECOLOGICAL SURVEY, 2010, 65 (09) : 571 - 572