Total Synthesis of the Neoclerodane Diterpene Salvinorin A via an Intramolecular Diels-Alder Strategy

被引：12
|
作者：
Wang, Yuzhou [1 ]
Metz, Peter [1 ]
机构：
[1] Tech Univ Dresden, Fak Chem & Lebensmittelchem, Organ Chem I, Bergstr 66, D-01069 Dresden, Germany
来源：
ORGANIC LETTERS | 2018年 / 20卷 / 11期
关键词：
KAPPA-OPIOID RECEPTOR; SALVIA-DIVINORUM; AGONIST; PRODUCTS; REAGENT; MICE;
D O I：
10.1021/acs.orglett.8b01357
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A concise total synthesis of the neoclerodane diterpene salvinorin A from 3-furaldehyde is reported using two highly diastereoselective intramolecular Diels-Alder reactions (IMDA) as the key transformations.
引用
收藏
页码：3418 / 3421
页数：4
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