Bioactive Compounds and Biological Functions of Garlic (Allium sativum L.)

被引：462
|
作者：
Shang, Ao [1 ]
Cao, Shi-Yu [1 ]
Xu, Xiao-Yu [1 ]
Gan, Ren-You [2 ,3 ]
Tang, Guo-Yi [1 ]
Corke, Harold [2 ]
Mavumengwana, Vuyo [4 ]
Li, Hua-Bin [1 ]
机构：
[1] Sun Yat Sen Univ, Sch Publ Hlth, Dept Nutr, Guangdong Prov Key Lab Food Nutr & Hlth, Guangzhou 510080, Guangdong, Peoples R China
[2] Shanghai Jiao Tong Univ, Sch Agr & Biol, Dept Food Sci & Technol, Shanghai 200240, Peoples R China
[3] Chinese Acad Agr Sci, Inst Urban Agr, Chengdu 610213, Sichuan, Peoples R China
[4] Stellenbosch Univ, DST NRF Ctr Excellence Biomed TB Res, Div Mol Biol & Human Genet, Dept Biomed Sci,Fac Med & Hlth Sci,US SAMRC Ctr T, ZA-8000 Cape Town, South Africa
来源：
FOODS | 2019年 / 8卷 / 07期
基金：
国家重点研发计划;
关键词：
garlic; phytochemicals; organic sulfides; health benefits; antioxidant; anticancer; cardiovascular protection; antimicrobial; TOTAL PHENOLIC CONTENTS; INDUCED LIVER-INJURY; S-ALLYL CYSTEINE; ANTIOXIDANT CAPACITIES; SIGNALING PATHWAY; OXIDATIVE STRESS; NATURAL-PRODUCTS; HEME OXYGENASE-1; BLOOD-PRESSURE; GASTRIC-ULCER;
D O I：
10.3390/foods8070246
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
Garlic (Allium sativum L.) is a widely consumed spice in the world. Garlic contains diverse bioactive compounds, such as allicin, alliin, diallyl sulfide, diallyl disulfide, diallyl trisulfide, ajoene, and S-allyl-cysteine. Substantial studies have shown that garlic and its bioactive constituents exhibit antioxidant, anti-inflammatory, antibacterial, antifungal, immunomodulatory, cardiovascular protective, anticancer, hepatoprotective, digestive system protective, anti-diabetic, anti-obesity, neuroprotective, and renal protective properties. In this review, the main bioactive compounds and important biological functions of garlic are summarized, highlighting and discussing the relevant mechanisms of actions. Overall, garlic is an excellent natural source of bioactive sulfur-containing compounds and has promising applications in the development of functional foods or nutraceuticals for the prevention and management of certain diseases.
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页数：31
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