Inner ear drug delivery using liposomes

被引：3

作者：

Mohammadian, F. ^{[1
]}

Eatemadi, A. ^{[2
,3
]}

Daraee, H. ^{[2
,3
]}

机构：

[1] Tabriz Univ Med Sci, Fac Adv Med Sci, Dept Med Biotechnol, Tabriz, Iran

[2] Univ Tehran Med Sci, Sch Adv Sci Med, Dept Med Biotechnol, Tehran, Iran

[3] Lorestan Univ Med Sci, Sch Med, Dept Med Biotechnol, Lorestan, Iran

来源：

CELLULAR AND MOLECULAR BIOLOGY | 2017年 / 63卷 / 01期

关键词：

Drug delivery; Liposome; Cochlea; Inner ear; SENSORINEURAL HEARING-LOSS; ROUND WINDOW MEMBRANE; SPIRAL-GANGLION NEURONS; GUINEA-PIG COCHLEA; GENE-TRANSFER; IN-VIVO; INTRATYMPANIC DEXAMETHASONE; TRANSGENE EXPRESSION; MENIERES-DISEASE; THERAPY;

D O I：

10.14715/cmb/2017.63.1.6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Dysfunction of inner ear can result in from several disease procedures and introduce a possibility for therapeutic intervention. The existence of a blood-cochlear obstacle and round window membrane restricts direct access into the inner ear and following inner ear drug, gene, protein and cell delivery. Several strategies have designed to increase drug delivery to the inner ear. One of main particles for inner ear drug delivery is liposome. Here we reviewed the application of liposomes in inner ear drug delivery.

引用

页码：28 / 33

页数：6

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