Picolinimidoamide-Cu(II) complex anchored on Fe3O4@SiO2 core-shell magnetic nanoparticles: an efficient reusable catalyst for click reaction

A Cu(II) complex supported on Fe3O4@SiO2 core-shell magnetic nanoparticles (MNPs) was prepared and characterized by FT-IR, XRD, SEM, EDX, TEM, VSM, TGA, and AAS analysis. The load of Cu on picolinimidoamide ligand anchored on Fe3O4@SiO2 core-shell MNPs was determined as 1.22, 1.54, and 1.70 wt% using AAS, EDX and TGA analyses, respectively. Synthesized Cu(II) complex on Fe3O4@SiO2 MNPs efficiently catalyzed a click reaction between alkyl halides, alkynes, and sodium azide to synthesize corresponding triazoles in high to excellent yields. The catalyst was recovered using an external magnetic field, and recycled for subsequent reactions without substantial loss of efficiency. [GRAPHICS] .