Xylaropyrones B and C, new γ-pyrones from the endophytic fungus Xylaria sp SC1440

被引：13
|
作者：
Guo, Chenjia
Wu, Ping
Xue, Jinghua
Li, Hanxiang [1 ]
Wei, Xiaoyi
机构：
[1] Chinese Acad Sci, Key Lab Plant Resources Conservat & Sustainable U, Guangzhou, Guangdong, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2018年 / 32卷 / 13期
基金：
中国国家自然科学基金;
关键词：
gamma-pyrones; endophytic fungus; Xylaria sp; secondary metabolites; CYTOTOXIC CONSTITUENTS; SECONDARY METABOLITES; COUPLING-CONSTANTS;
D O I：
10.1080/14786419.2017.1385013
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Two new -pyrones, xylaropyrones B (1) and C (2), together with three known compounds, xylaropyrone (3), annularin A (4) and annularin C (5), were isolated from solid cultures of the endophytic fungus Xylaria sp. SC1440. The structures of these compounds were determined mainly by analysis of their NMR spectroscopic data. The relative configurations of 1 and 2 were assigned on the basis of J-based configurational analysis, and the absolute configurations were established by experimental and TDDFT calculated ECD spectra. The isolated compounds were evaluated for cytotoxic and tyrosinase inhibitory activity. [GRAPHICS] .
引用
收藏
页码：1525 / 1531
页数：7
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