MacA a diheme c-type cytochrorne involved in Fe(III) reduction by Geobacter sulfurreducens

被引:87
|
作者
Butler, JE [1 ]
Kaufmann, F [1 ]
Coppi, MV [1 ]
Núñez, C [1 ]
Lovley, DR [1 ]
机构
[1] Univ Massachusetts, Dept Microbiol, Amherst, MA 01003 USA
关键词
D O I
10.1128/JB.186.12.4042-4045.2004
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A 36-kDa diheme c-type cytochrome abundant in Fe(III)-respiring Geobacter sulfurreducens, designated MacA, was more highly expressed during growth with Fe(III) as the electron acceptor than with fumarate. Although MacA has homology to proteins with in vitro peroxidase activity, deletion of macA had no impact on response to oxidative stress. However, the capacity for Fe(III) reduction was greatly diminished, indicating that MacA, which is predicted to be localized in the periplasm, is a key intermediate in electron transfer to Fe(III).
引用
收藏
页码:4042 / 4045
页数:4
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