Case of Pediatric Bullous Systemic Lupus Erythematosus Treated with Intravenous Immunoglobulin

被引：8

作者：

Juhasz, Margit ^{[1
]}

Rogge, Megan ^{[2
]}

Chen, Mary ^{[2
]}

Czernik, Annette ^{[2
]}

Kim, Soo Jung ^{[2
]}

Geller, Lauren ^{[2
,3
]}

机构：

[1] Icahn Sch Med Mt Sinai, 1 Gustave L Levy Pl, New York, NY 10029 USA

[2] Icahn Sch Med Mt Sinai, Dept Dermatol, New York, NY 10029 USA

[3] Icahn Sch Med Mt Sinai, Dept Pediat, New York, NY 10029 USA

来源：

PEDIATRIC DERMATOLOGY | 2017年 / 34卷 / 01期

关键词：

UPDATE;

D O I：

10.1111/pde.13015

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

This is a case report of a 16-year-old girl recently diagnosed with systemic lupus erythematosus (SLE) who presented with multiple blisters on the face, hands, arms, legs, trunk, and vaginal and oral mucosa. Skin biopsy was consistent with bullous SLE (BSLE). Dapsone is often the first-line treatment option for BSLE, but the patient's history of anemia and leukopenia and long-term immunosuppression requirement for her systemic symptoms raised concerns about dapsone and bone marrow toxicity, especially hemolytic anemia and agranulocytosis. She was started on intravenous immunoglobulin (IVIG), 2 g/kg divided over 3 days, with significant improvement in her cutaneous symptoms. IVIG is a treatment option for BSLE patients in whom agents such as dapsone are contraindicated.

引用

页码：E54 / E56

页数：3

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