Control strategies for removing difficult host cell proteins in monoclonal antibody processing

被引:0
|
作者
Welsh, John [1 ]
Han, InKwan [1 ]
Pollard, Jennifer [1 ]
Roush, David [1 ]
Tugcu, Nihal [1 ]
机构
[1] Merck & Co Inc, Kenilworth, NJ USA
来源
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2019年 / 257卷
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
180
引用
收藏
页数:1
相关论文
共 50 条
  • [41] ANALYSIS OF MONOCLONAL-ANTIBODY PROCESSING AFTER BINDING TO ANTIGEN ON THE TUMOR-CELL SURFACE
    MATZKU, S
    DIPPOLD, WG
    BRUGGEN, J
    SCHIRRMACHER, V
    TILGEN, W
    JOURNAL OF CELLULAR BIOCHEMISTRY, 1986, : 76 - 76
  • [42] Exploitation of the adsorptive properties of depth filters for host cell protein removal during monoclonal antibody purification
    Yigzaw, Y
    Piper, R
    Tran, M
    Shukla, AA
    BIOTECHNOLOGY PROGRESS, 2006, 22 (01) : 288 - 296
  • [43] Improved Host Cell Protein Analysis in Monoclonal Antibody Products through Molecular Weight Cutoff Enrichment
    Chen, I-Hsuan
    Xiao, Hui
    Daly, Thomas
    Li, Ning
    ANALYTICAL CHEMISTRY, 2020, 92 (05) : 3751 - 3757
  • [44] Characterization of chinese hamster ovary host cell protein interactions with monoclonal antibody by yeast surface display
    McGovern, Colleen
    Doolan, Kyle
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
  • [45] BIOT 180-Using cationic polyelectrolytes to precipitate host cell impurities in monoclonal antibody purification
    Peram, Thanmaya
    McDonald, Paul
    Fahrner, Robert
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 238
  • [46] A MONOCLONAL-ANTIBODY TO ALPHA TUBULIN RECOGNIZES HOST-CELL AND TRYPANOSOMA-CRUZI TUBULINS
    PAULIN, JJ
    KEITH, CH
    TARLETON, RL
    JOURNAL OF PROTOZOOLOGY, 1988, 35 (01): : 123 - 129
  • [47] Cell Line-Specific Control of Recombinant Monoclonal Antibody Production by CHO Cells
    O'Callaghan, Peter M.
    McLeod, Jane
    Pybus, Leon P.
    Lovelady, Clare S.
    Wilkinson, Stephen J.
    Racher, Andrew J.
    Porter, Alison
    James, David C.
    BIOTECHNOLOGY AND BIOENGINEERING, 2010, 106 (06) : 938 - 951
  • [48] Validating clearance of DNA, host cell proteins and viruses for a human antibody purification process.
    Lauziere, K
    PerilliPalmer, B
    Stanley, K
    Fenton, B
    Grant, K
    Turner, B
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1997, 213 : 289 - BIOT
  • [49] Displacement to separate host-cell proteins and aggregates in cation-exchange chromatography of monoclonal antibodies
    Khanal, Ohnmar
    Kumar, Vijesh
    Lenhoff, Abraham M.
    BIOTECHNOLOGY AND BIOENGINEERING, 2021, 118 (01) : 164 - 174
  • [50] Mammalian cell surface display for monoclonal antibody-based FACS selection of viral envelope proteins
    Bruun, Tim-Henrik
    Grassmann, Veronika
    Zimmer, Benjamin
    Asbach, Benedikt
    Peterhoff, David
    Kliche, Alexander
    Wagner, Ralf
    MABS, 2017, 9 (07) : 1052 - 1064