Gas chromatographic enantiomer separation on long-chain alkylated β-cyclodextrin chiral stationary phases

被引：17
|
作者：
Nie, MY [1 ]
Zhou, LM [1 ]
Liu, XL [1 ]
Wang, QH [1 ]
Zhu, DQ [1 ]
机构：
[1] Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116012, Peoples R China
来源：
ANALYTICA CHIMICA ACTA | 2000年 / 408卷 / 1-2期
基金：
中国国家自然科学基金;
关键词：
enantiomer separation; cyclodextrin derivatives; capillary gas chromatography; chiral stationary phases;
D O I：
10.1016/S0003-2670(99)00804-1
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Two new chiral stationary phases, heptakis(2,6-di-O-nonyl-3-O-trifluoroacetyl)-beta-cyclodextrin (DNTBCD) and heptakis(2,6-di-O-dodecyl-3-O-trifluoroacetyl)-beta-cyclodextrin (DDTBCD), were synthesized. The gas chromatographic enantiomeric separation of amines, alcohols, diols, carboxylic acids, amino acids, epoxides, halohydrocarbons and ketones were investigated on DNTBCD, DDTBCD and heptakis(2,w6-di-O-npentyl-3-O-trifluoroacetyl)-beta-cyclodextrin (DPTBCD) stationary phases. It is observed that DNTBCD exhibits the best chiral selectivity among three stationary phases for most racemates investigated. An enthalpy-entropy compensation effect exists within the a-phenylethylamine derivatives separated on DPTBCD and DNTBCD stationary phases. (C) 2000 Elsevier Science B.V. All rights reserved.
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页码：279 / 284
页数：6
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