Separation of NADH-fumarate reductase and succinate dehydrogenase activities in Trypanosoma cruzi

被引：0
|
作者：
Christmas, PB [1 ]
Turrens, JF [1 ]
机构：
[1] Univ S Alabama, Dept Biomed Sci, Coll Allied Hlth Profess, Mobile, AL 36688 USA
来源：
FEMS MICROBIOLOGY LETTERS | 2000年 / 183卷 / 02期
关键词：
Trypanosoma cruzi; NADH-fumarate reductase; succinate dehydrogenase; electron transfer; mitochondria; metabolism;
D O I：
10.1016/S0378-1097(99)00646-1
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
A recent review suggested that the activity of NADH-fumarate reductase from trypanosomatids could be catalyzed by succinate dehydrogenase working in reverse (Tielens and van Hellemond, Parasitol. Today 14, 265-271, 1999). The results reported in this study demonstrate that the two activities can easily be separated without any loss in either activity, suggesting that fumarate reductase and succinate dehydrogenase are separate enzymes. (C) 2000 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.
引用
收藏
页码：225 / 228
页数：4
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