Is the progress zone model a victim of progress?

被引:18
|
作者
Saunders, JW
机构
[1] Box 3381, Waquoit
关键词
D O I
10.1016/S0092-8674(02)00936-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The prevailing view has long been that mesenchymal cells at the apex of the vertebrate limb bud proliferate in a progress zone (PZ) under the influence of the apical ectodermal ridge (AER). According to the PZ model, proximodistal cell fates are specified according to the time spent in the PZ. New results, considered along with some earlier findings, fail to support this model.
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页码:541 / 543
页数:3
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