MEDICINAL CHEMISTRY PERSPECTIVES FOR THE 21ST CENTURY: CHALLENGES AND OPPROTUNITIES

被引：6
|
作者：
Andrade, Carolina Horta [1 ]
Kummerle, Arthur E. [2 ]
Guido, Rafael V. C. [3 ]
机构：
[1] Univ Fed Goias, Fac Farm, Rua 240,Qd 87,St Leste Univ, BR-74605170 Goiania, Go, Brazil
[2] Univ Fed Rural Rio de Janeiro, Dept Quim, BR-23897000 Seropedica, RJ, Brazil
[3] Univ Sao Paulo, Inst Fis Sao Carlos, Av Joao Dagnone 1100, BR-13563120 Sao Carlos, SP, Brazil
来源：
QUIMICA NOVA | 2018年 / 41卷 / 04期
基金：
巴西圣保罗研究基金会;
关键词：
Medicinal Chemistry; perspectives; future; challenges; MULTIDRUG-RESISTANT; ZIKA VIRUS; DRUG; MICROFLUIDICS; DISEASES; FUTURE;
D O I：
10.21577/0100-4042.20170182
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
In the 21st century, medicinal chemists will face many challenges to improve the quality of life of populations. The challenges consist of emerging infectious (ex. bacterial, viral and parasite infections) and non-communicable diseases (ex. autoimmune, Alzheimer disease, Parkinson's disease) that will require innovative technologies (ex. microfluidics, nanotechnology, biotechnology) to be fully understood and combated. In this work, we indicate trends, perspectives and opportunities related to drug discovery as well as highlight the tools and strategies that could be used in drug discovery of the 21st century.
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页码：476 / 483
页数：8
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