MEDICINAL CHEMISTRY PERSPECTIVES FOR THE 21ST CENTURY: CHALLENGES AND OPPROTUNITIES

被引：6

作者：

Andrade, Carolina Horta ^{[1
]}

Kummerle, Arthur E. ^{[2
]}

Guido, Rafael V. C. ^{[3
]}

机构：

[1] Univ Fed Goias, Fac Farm, Rua 240,Qd 87,St Leste Univ, BR-74605170 Goiania, Go, Brazil

[2] Univ Fed Rural Rio de Janeiro, Dept Quim, BR-23897000 Seropedica, RJ, Brazil

[3] Univ Sao Paulo, Inst Fis Sao Carlos, Av Joao Dagnone 1100, BR-13563120 Sao Carlos, SP, Brazil

来源：

QUIMICA NOVA | 2018年 / 41卷 / 04期

基金：

巴西圣保罗研究基金会;

关键词：

Medicinal Chemistry; perspectives; future; challenges; MULTIDRUG-RESISTANT; ZIKA VIRUS; DRUG; MICROFLUIDICS; DISEASES; FUTURE;

D O I：

10.21577/0100-4042.20170182

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In the 21st century, medicinal chemists will face many challenges to improve the quality of life of populations. The challenges consist of emerging infectious (ex. bacterial, viral and parasite infections) and non-communicable diseases (ex. autoimmune, Alzheimer disease, Parkinson's disease) that will require innovative technologies (ex. microfluidics, nanotechnology, biotechnology) to be fully understood and combated. In this work, we indicate trends, perspectives and opportunities related to drug discovery as well as highlight the tools and strategies that could be used in drug discovery of the 21st century.

引用

页码：476 / 483

页数：8

共 50 条

[1] Medicinal Chemistry in the 21st Century
Augustyns, Koen
Ecker, Gerhard
[J]. MEDCHEMCOMM, 2010, 1 (01) : B5 - B7
[2] Perspectives and challenges for desalination in the 21st century
Schiffler, M
[J]. DESALINATION, 2004, 165 (1-3) : 1 - 9
[3] The challenges of inorganic chemistry in the 21st century
Navratil, JD
[J]. SOUTH AFRICAN JOURNAL OF CHEMISTRY-SUID-AFRIKAANSE TYDSKRIF VIR CHEMIE, 1998, 51 (02): : 64 - 65
[4] Cements in the 21st century: Challenges, perspectives, and opportunities
Biernacki, Joseph J.
Bullard, Jeffrey W.
Sant, Gaurav
Brown, Kevin
Glasser, Fredrik P.
Jones, Scott
Ley, Tyler
Livingston, Richard
Nicoleau, Luc
Olek, Jan
Sanchez, Florence
Shahsavari, Rouzbeh
Stutzman, Paul E.
Sobolev, Konstantine
Prater, Tracie
[J]. JOURNAL OF THE AMERICAN CERAMIC SOCIETY, 2017, 100 (07) : 2746 - 2773
[5] Electromagnetic engineering in the 21st century: Challenges and perspectives
Felsen, Leopold B.
Sevgi, Levent
[J]. Turkish Journal of Electrical Engineering and Computer Sciences, 2002, 10 (02) : 131 - 145
[6] The challenges and opportunity of theoretical chemistry of the 21st century
Xu, GX
[J]. CHINESE JOURNAL OF STRUCTURAL CHEMISTRY, 2002, 21 (05) : 463 - 469
[7] The Perspectives and Challenges of Applied Anthropology in the 21st Century
Marisol Perez, L.
[J]. REVISTA MAD-REVISTA DEL MAGISTER EN ANALISIS SISTEMICO APLICADO A LA SOCIEDAD, 2007, (17): : 1 - 9
[8] Chemistry for the 21st century
Keinan, Ehud
Schechter, Israel
[J]. Journal of Chemical Education, 2002, 79 (01)
[9] 21st century challenges
不详
[J]. REVISTA DE HISPANISMO FILOSOFICO, 2008, (13): : 238 - 238
[10] Tackling Grand Challenges of the 21st Century with Electroanalytical Chemistry
[J]. Peng, Zhangquan (zqpeng@ciac.ac.cn), 1600, American Chemical Society (140):

← 1 2 3 4 5 →