Palladium-catalyzed three-component reaction of N-tosyl hydrazones, isonitriles and amines leading to amidines

被引：50
|
作者：
Dai, Qiang [1 ]
Jiang, Yan [1 ]
Yu, Jin-Tao [1 ]
Cheng, Jiang [1 ]
机构：
[1] Changzhou Univ, Jiangsu Key Lab Adv Catalyt Mat & Technol, Sch Petrochem Engn, Jiangsu Prov Key Lab Fine Petrochem Engn, Changzhou 213164, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 93期
基金：
中国国家自然科学基金;
关键词：
EFFICIENT SYNTHESIS; GUANIDINES; INHIBITORS; CHEMISTRY; ALKYNE;
D O I：
10.1039/c5cc06771e
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A palladium-catalyzed three-component reaction between N-tosyl hydrazones, aryl isonitriles and amines was developed, leading to amidines in moderate to good yields. This procedure features the rapid construction of amidine frameworks with high diversity and complexity. Ketenimines serve as intermediates, which encounter nucleophilic attack by amines to produce amidines.
引用
收藏
页码：16645 / 16647
页数：3
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