A genome-wide and nonredundant mouse transcription factor database

被引:105
|
作者
Kanamori, M
Konno, H
Osato, N
Kawai, J
Hayashizaki, Y
Suzuki, H
机构
[1] RIKEN, GSC, Lab Genome Explorat Res Grp, Tsurumi Ku, Yokohama, Kanagawa 2300045, Japan
[2] RIKEN, Genome Sci Lab, Wako, Saitama 3510198, Japan
关键词
mouse; transcription factor; database; gene ontology; LocusLink; annotation; cDNA clones;
D O I
10.1016/j.bbrc.2004.07.179
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Here we describe the development of a genome-wide and nonredundant mouse transcription factor database and its viewer (http://genome.gsc.riken.jp/TFdb/). We systematically selected transcription factors with DNA-binding properties and their regulators on the basis of their LocusLink and Gene Ontology annotations. We also incorporated into our database information regarding the corresponding available cDNA clones and their structural properties. Because of these features, our database is unique and may provide useful information for systematic genome-wide studies of transcriptional regulation. (C) 2004 Elsevier Inc. All rights reserved.
引用
收藏
页码:787 / 793
页数:7
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