Phyllodes Tumor in Survivors of Childhood Osteosarcoma: A Single Institution's Experience

被引：4

作者：

Jaing, Tang-Her ^{[1
]}

Yang, Chao-Ping ^{[1
]}

Hung, Iou-Jih ^{[1
]}

Chen, Shih-Hsiang ^{[1
]}

Tang, Tzung-Chih ^{[2
]}

Shih, Hsin-Nung ^{[3
]}

Hsueh, Chuen ^{[4
]}

机构：

[1] Chang Gung Univ, Chang Gung Childrens Hosp, Div Hematol Oncol, Dept Pediat, Taoyuan 333, Taiwan

[2] Chang Gung Univ, Chang Gung Mem Hosp, Div Hematol Oncol, Dept Internal Med, Taoyuan 333, Taiwan

[3] Chang Gung Univ, Chang Gung Mem Hosp, Dept Orthoped Surg, Div Joint Reconstruct, Taoyuan 333, Taiwan

[4] Chang Gung Univ, Chang Gung Mem Hosp, Dept Pathol, Taoyuan 333, Taiwan

来源：

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2014年 / 36卷 / 01期

关键词：

osteosarcoma survivor; phyllodes tumor; second neoplasms; 2ND MALIGNANT NEOPLASMS; LI-FRAUMENI SYNDROME; LOCAL RECURRENCE; FOLLOW-UP; CANCER; BREAST; CHEMOTHERAPY;

D O I：

10.1097/MPH.0b013e3182a6d4a4

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We evaluate the incidence of second neoplasms in 86 patients with osteosarcoma (OS) of the extremities treated with different protocols of adjuvant chemotherapy. Three patients developed phyllodes tumors as the second neoplasm. One of these patients simultaneously developed a third cancer with therapy-related acute myeloid leukemia. The sites of primary OS were the tibia (2) and humerus (1). None had received prior radiotherapy before excision of phyllodes tumor. All the patients were female with a median age of 21.7 years at the time of presentation. As yet, that precise causation is unclear, but it can increase our understanding of carcinogenic processes, in general.

引用

页码：E36 / E38

页数：3

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