Direct condensation of functionalized sp3 carbons with formanilides for enamine synthesis using an in situ generated HMDS amide catalyst

被引：26
|
作者：
Taneda, Hiroshi [1 ]
Inamoto, Kiyofumi [1 ]
Kondo, Yoshinori [1 ]
机构：
[1] Tohoku Univ, Grad Sch Pharmaceut Sci, Aoba Ku, Sendai, Miyagi 9808578, Japan
来源：
CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 49期
基金：
日本学术振兴会;
关键词：
EFFICIENT; ACID; DERIVATIVES; ESTERS; AGENTS;
D O I：
10.1039/c4cc02228a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The efficient synthesis of functionalized enamines including beta-enaminoesters was effectively accomplished by the direct condensation of functionalized sp(3) carbanions such as acetates with formamides using in situ generated HMDS base from catalytic cesium fluoride and stoichiometric tristrimethylsilylamine.
引用
收藏
页码：6523 / 6525
页数：3
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