Lifeline for the front lines: blood products to support the warfighter

被引：6

作者：

Taylor, Audra L. ^{[1
]}

Corley, Jason B. ^{[2
]}

Swingholm, Matthew T. ^{[2
]}

Sloan, Melanie A. ^{[3
]}

McDonald, Harry, Jr. ^{[4
]}

Quesada, Jose F. ^{[5
]}

Evans, Christopher L. ^{[6
]}

Ceballos, William A. ^{[7
]}

机构：

[1] Def Hlth Agcy, Armed Serv Blood Program, Falls Church, VA USA

[2] US Army, Med Command, Army Blood Program, Jbsa Ft Sam Houston, TX 78219 USA

[3] Womack Army Med Ctr, Dept Pathol, Ft Bragg, NC USA

[4] US Army, Inst Surg Res, Jbsa Ft Sam Houston, TX USA

[5] Dept Def, Med Educ & Training Campus, Jbsa Ft Sam Houston, TX USA

[6] Landstuhl Reg Med Ctr, Dept Pathol, Landstuhl, Germany

[7] 432nd Med Detachment Blood Support, Ft Bragg, NC USA

来源：

TRANSFUSION | 2019年 / 59卷

关键词：

WHOLE-BLOOD;

D O I：

10.1111/trf.15165

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

BACKGROUNDHemorrhage is the leading cause of death on the battlefield. Damage control resuscitation guidelines in the US military recommend whole blood as the preferred resuscitation product. The Armed Services Blood Program (ASBP) has initiated low-titer group O whole blood (LTOWB) production and predeployment donor screening to make whole blood more available to military forces. STUDY DESIGN AND METHODSASBP donor centers updated procedures and labeling for LTOWB production. Donors are screened according to US Food and Drug Administration regulations and standard operating procedures. Group O donors are tested for anti-A and anti-B titer levels. Additionally, military personnel notified for pending deployment coordinate with their local ASBP donor center to complete whole blood donor prescreening. The process consists of completing a donor history questionnaire, processing of blood samples for blood group and infectious disease testing, and titer determination for group O personnel. RESULTSSince March 2016, 7940 LTOWB units have been manufactured at ASBP donor centers and shipped in support of combat operations. Additionally, ASBP donor centers have screened several thousand service members before deployment. From these screenings, the donor low titer rate was 68% and infectious disease reactive test rate was extremely low (0.004). CONCLUSIONWhole blood is now the preferred blood product for resuscitation of combat trauma patients. The ASBP partnered with combat forces to screen personnel before deployment. Additionally, LTOWB is manufactured and shipped in support of combat operations. These efforts are expanding the availability of LTOWB for the warfighter.

引用

页码：1453 / 1458

页数：6

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