This study, using a secondary dataset from the 2002 National Study of the Changing Workforce, examines how working parents cope with work demands and family responsibilities. The design is a study on the relationships of flexible work schedule, workplace support, supervisory support, and work-life balance on the well-being of working parents employing the Structural Equation Model (SEM). In this study, employee well-being is an endogenous latent construct. Work-schedule flexibility, workplace support, supervisory support, and work-life balance are latent exogenous constructs. This information will assist social workers in developing more effective intervention efforts in the workplace, with the ultimate goal of increasing the quality of life.