Anodic fabrication and bioactivity of Nb-doped TiO2 nanotubes

被引:33
|
作者
Ding, Dongyan [2 ]
Ning, Congqin [1 ]
Huang, Lin [1 ,2 ]
Jin, Fangchun [3 ]
Hao, Yongqiang [3 ]
Bai, Shuo [2 ]
Li, Yan [2 ]
Li, Ming [2 ]
Mao, Dali [2 ]
机构
[1] Chinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, Shanghai 200050, Peoples R China
[2] Shanghai Jiao Tong Univ, Sch Mat Sci & Engn, Lab Microelect Mat & Technol, State Key Lab Met Matrix Composites, Shanghai 200240, Peoples R China
[3] Shanghai Jiao Tong Univ, Sch Med, Peoples Hosp 9, Shanghai 200011, Peoples R China
关键词
GROWTH; ANODIZATION;
D O I
10.1088/0957-4484/20/30/305103
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
We report anodic formation of Ti-Nb-O nanotubes on top of a Ti35Nb alloy, and in vitro bioactivity and stem cell response of the anodic nanotubes. It was found that the amorphous Ti-Nb-O nanotubes presented a significantly enhanced in vitro bioactivity (in simulated body fluids) compared to those of undoped TiO2 nanotubes and porous Ti-Nb-O without nanotubular structure. Similar to undoped TiO2 nanotubes, the Ti-Nb-O nanotubes also promote mesenchymal stem cell adhesion and fast formation of extracellular matrix (ECM) materials. The above findings make it possible to further explore the biological properties, such as cell proliferation and drug delivery, of a variety of Ti-alloy-based oxide nanotubes.
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页数:6
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