Modifying histories and initiating meiotic recombination: New answers to an old question

被引:10
|
作者
Maleki, S [1 ]
Keeney, S [1 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Program Mol Biol, New York, NY 10021 USA
关键词
D O I
10.1016/j.cell.2004.08.008
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
It is well documented that the formation of the DNA double-strand breaks (DSBs) that initiate meiotic recombination is influenced by chromatin and larger scale chromosome organization, but the molecular nature of this influence has remained elusive. Several recent studies, including Reddy and Villeneuve (2004, this issue of Cell), shed light on this issue by revealing roles for posttranslational histone modifications in promoting DSB formation.
引用
收藏
页码:404 / 406
页数:3
相关论文
共 50 条
  • [1] New and old ways to control meiotic recombination
    Phadnis, Naina
    Hyppa, Randy W.
    Smith, Gerald R.
    TRENDS IN GENETICS, 2011, 27 (10) : 411 - 421
  • [2] What Is an Author? Old Answers to a New Question
    Helle, Sophus
    MODERN LANGUAGE QUARTERLY, 2019, 80 (02): : 113 - 139
  • [3] Is handedness related to anxiety? New answers to an old question
    Lyle, Keith B.
    Chapman, L. Kevin
    Hatton, Jessica M.
    LATERALITY, 2013, 18 (05): : 520 - 535
  • [4] Is there a language beyond speech? New answers to an old question
    Schmolders, C
    MERKUR-DEUTSCHE ZEITSCHRIFT FUR EUROPAISCHES DENKEN, 2003, 57 (07): : 619 - 624
  • [5] ELECTROCONVULSIVE-THERAPY - OLD QUESTION, NEW ANSWERS
    ALLEN, RM
    PSYCHIATRIC ANNALS, 1978, 8 (05) : 47 - &
  • [6] NEW ANSWERS TO AN OLD QUESTION - WOMANS PLACE IS IN WHAT
    STULL, RA
    PERSONNEL JOURNAL, 1973, 52 (01) : 31 - 35
  • [7] Compliance with drug therapy -: new answers to an old question
    Düsing, R
    Lottermoser, K
    Mengden, T
    NEPHROLOGY DIALYSIS TRANSPLANTATION, 2001, 16 (07) : 1317 - 1321
  • [8] Serum or plasma? An old question looking for new answers
    Plebani, Mario
    Banfi, Giuseppe
    Bernardini, Sergio
    Bondanini, Francesco
    Conti, Laura
    Dorizzi, Romolo
    Ferrara, Fulvio Enrico
    Mancini, Rita
    Trenti, Tommaso
    CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2020, 58 (02) : 178 - 187
  • [9] Rethinking tamoxifen in the management of melanoma: New answers for an old question
    Ribeiro, Mariana P. C.
    Santos, Armanda E.
    Custodio, Jose B. A.
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2015, 764 : 372 - 378
  • [10] The synaptonemal complex and meiotic recombination in humans: new approaches to old questions
    Vallente, RU
    Cheng, EY
    Hassold, TJ
    CHROMOSOMA, 2006, 115 (03) : 241 - 249