The merits of the ICD for inherited heart rhythm disorders: A critical re-appraisal

被引:1
|
作者
Roston, Thomas M. [1 ,2 ]
Krahn, Andrew D. [1 ]
Ong, Kevin [1 ]
Sanatani, Shubhayan [3 ]
机构
[1] Univ British Columbia, Dept Med, Div Cardiol, 1081 Burrard St, Vancouver, BC V6Z 1Y6, Canada
[2] Univ Alberta, Dept Med, 13-103 Clin Sci Bldg,11350-83 Ave, Edmonton, AB T6G 2G3, Canada
[3] Univ British Columbia, Dept Pediat, Div Cardiol, 4480 Oak St,1F Clin, Vancouver, BC V6H 0B3, Canada
基金
加拿大健康研究院;
关键词
Implantable cardioverter defibrillator; Inherited arrhythmia; Long QT syndrome; Brugada syndrome; Arrhythmogenic; Right ventricular; Cardiomyopathy; POLYMORPHIC VENTRICULAR-TACHYCARDIA; LONG-QT-SYNDROME; SUDDEN CARDIAC DEATH; IMPLANTABLE CARDIOVERTER-DEFIBRILLATORS; HIGH-RISK PATIENTS; ARRHYTHMIC EVENTS; BRUGADA-SYNDROME; SYMPATHETIC DENERVATION; MOLECULAR CHARACTERIZATION; MISSENSE MUTATION;
D O I
10.1016/j.tcm.2019.10.004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The implantable cardioverter defibrillator (ICD) is often considered a routine intervention for an inherited heart rhythm disorder (IHRD) despite there being little to no randomized data for non-ischemic indications. Furthermore, existing IHRD studies often do not report adverse ICD outcomes, and observational data increasingly show that complications are under-recognized. Only recently have tools emerged to address the rational use of ICDs for specific forms of IHRD, although the acceptable risk of device complications remains unestablished. Here, we summarize the evidence of ICD benefit and harm in IHRD, highlight current knowledge gaps, and propose alternative and adjunctive options to the transvenous ICD. (C) 2019 Published by Elsevier Inc.
引用
收藏
页码:415 / 421
页数:7
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