The merits of the ICD for inherited heart rhythm disorders: A critical re-appraisal
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作者:
Roston, Thomas M.
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Univ British Columbia, Dept Med, Div Cardiol, 1081 Burrard St, Vancouver, BC V6Z 1Y6, Canada
Univ Alberta, Dept Med, 13-103 Clin Sci Bldg,11350-83 Ave, Edmonton, AB T6G 2G3, CanadaUniv British Columbia, Dept Med, Div Cardiol, 1081 Burrard St, Vancouver, BC V6Z 1Y6, Canada
Roston, Thomas M.
[1
,2
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Krahn, Andrew D.
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Univ British Columbia, Dept Med, Div Cardiol, 1081 Burrard St, Vancouver, BC V6Z 1Y6, CanadaUniv British Columbia, Dept Med, Div Cardiol, 1081 Burrard St, Vancouver, BC V6Z 1Y6, Canada
Krahn, Andrew D.
[1
]
Ong, Kevin
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Univ British Columbia, Dept Med, Div Cardiol, 1081 Burrard St, Vancouver, BC V6Z 1Y6, CanadaUniv British Columbia, Dept Med, Div Cardiol, 1081 Burrard St, Vancouver, BC V6Z 1Y6, Canada
Ong, Kevin
[1
]
Sanatani, Shubhayan
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Univ British Columbia, Dept Pediat, Div Cardiol, 4480 Oak St,1F Clin, Vancouver, BC V6H 0B3, CanadaUniv British Columbia, Dept Med, Div Cardiol, 1081 Burrard St, Vancouver, BC V6Z 1Y6, Canada
Sanatani, Shubhayan
[3
]
机构:
[1] Univ British Columbia, Dept Med, Div Cardiol, 1081 Burrard St, Vancouver, BC V6Z 1Y6, Canada
The implantable cardioverter defibrillator (ICD) is often considered a routine intervention for an inherited heart rhythm disorder (IHRD) despite there being little to no randomized data for non-ischemic indications. Furthermore, existing IHRD studies often do not report adverse ICD outcomes, and observational data increasingly show that complications are under-recognized. Only recently have tools emerged to address the rational use of ICDs for specific forms of IHRD, although the acceptable risk of device complications remains unestablished. Here, we summarize the evidence of ICD benefit and harm in IHRD, highlight current knowledge gaps, and propose alternative and adjunctive options to the transvenous ICD. (C) 2019 Published by Elsevier Inc.
机构:
St Petersburg State Univ, Inst Translat Biomed, St Petersburg, Russia
Almazov Natl Med Res Ctr, Inst Expt Med, St Petersburg, Russia
Granov Russian Sci Ctr Radiol & Surg Technol, St Petersburg, RussiaUniv Passo Fundo UPF, Biosci Inst, Passo Fundo, RS, Brazil
Lakstygal, Anton M.
Amstislavskaya, Tamara G.
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Sci Res Inst Physiol & Basic Med, Novosibirsk, Russia
Novosibirsk State Univ, Inst Med & Psychol, Novosibirsk, RussiaUniv Passo Fundo UPF, Biosci Inst, Passo Fundo, RS, Brazil
Amstislavskaya, Tamara G.
Demin, Konstantin A.
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St Petersburg State Univ, Inst Translat Biomed, St Petersburg, Russia
Almazov Natl Med Res Ctr, Inst Expt Med, St Petersburg, RussiaUniv Passo Fundo UPF, Biosci Inst, Passo Fundo, RS, Brazil
机构:
North West Univ, Ctr Excellence Pharmaceut Sci, Sch Pharm, Potchefstroom, South AfricaUniv Passo Fundo UPF, Biosci Inst, Passo Fundo, RS, Brazil
Vlok, Marli
Harvey, Brian H.
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North West Univ, Ctr Excellence Pharmaceut Sci, Sch Pharm, Potchefstroom, South AfricaUniv Passo Fundo UPF, Biosci Inst, Passo Fundo, RS, Brazil
Harvey, Brian H.
Piato, Angelo
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Int Zebrafish Neurosci Res Consortium ZNRC, Slidell, LA USA
Fed Univ Rio Grande UFRGS, Postgrad Program Neurosci, Porto Alegre, RS, BrazilUniv Passo Fundo UPF, Biosci Inst, Passo Fundo, RS, Brazil
Piato, Angelo
Barcellos, Leonardo J. G.
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Univ Passo Fundo UPF, Postgrad Program Environm Sci, Passo Fundo, RS, Brazil
Univ Passo Fundo UPF, Postgrad Program Bioexpt, Passo Fundo, RS, Brazil
Fed Univ Santa Maria UFSM, Postgrad Program Pharmacol, Santa Maria, RS, BrazilUniv Passo Fundo UPF, Biosci Inst, Passo Fundo, RS, Brazil
Barcellos, Leonardo J. G.
Kalueff, Allan, V
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Southwest Univ, Sch Pharm, Chongqing, Peoples R China
Ural Fed Univ, Ekaterinburg, RussiaUniv Passo Fundo UPF, Biosci Inst, Passo Fundo, RS, Brazil
机构:
Univ Pittsburgh, Div Transplantat Pathol, Dept Pathol, Thomas E Starzl Transplantat Inst, E737 UPMC Montefiore Hosp,3459 Fifth Ave, Pittsburgh, PA 15213 USAUniv Pittsburgh, Div Transplantat Pathol, Dept Pathol, Thomas E Starzl Transplantat Inst, E737 UPMC Montefiore Hosp,3459 Fifth Ave, Pittsburgh, PA 15213 USA