Human cathelicidin LL-37 increases vascular permeability in the skin via mast cell activation, and phosphorylates MAP kinases p38 and ERK in mast cells

被引:48
|
作者
Chen, XJ
Ikeda, S
Chen, XJ
Niyonsaba, F
Ushio, H
Okumura, K
Ogawa, H
Chen, XJ
Nagaoka, I
Okumura, K
机构
[1] Juntendo Univ, Sch Med, Dept Dermatol, Bunkyo Ku, Tokyo 1138421, Japan
[2] Juntendo Univ, Sch Med, Atopy Allergy Res Ctr, Bunkyo Ku, Tokyo 1138421, Japan
[3] Sichuan Prov Peoples Hosp, Dept Dermatol, Chengdu 610072, Sichuan, Peoples R China
[4] Juntendo Univ, Sch Med, Dept Host Def & Biochem Res, Bunkyo Ku, Tokyo 1138421, Japan
[5] Juntendo Univ, Sch Med, Dept Immunol, Bunkyo Ku, Tokyo 1138421, Japan
关键词
cathelicidin; mast cell; MAP kinase; degranulation; vascular permeability;
D O I
10.1016/j.jdermsci.2006.03.001
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
引用
收藏
页码:63 / 66
页数:4
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