Regioselective Oxidative Cross-Coupling Reaction: Synthesis of Imidazo[1,2-a]pyridine Fluorophores

被引：4

作者：

Chu, Xianglong ^{[1
]}

Niu, Yadi ^{[1
]}

Wang, Xiaodong ^{[2
]}

Lin, Yunliang ^{[2
]}

Li, Fuwei ^{[2
]}

Ma, Chen ^{[1
]}

机构：

[1] Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China

[2] Qilu Univ Technol, Shandong Anal & Test Ctr, Shandong Acad Sci, Jinan 250353, Peoples R China

来源：

SYNTHESIS-STUTTGART | 2021年 / 53卷 / 09期

基金：

中国国家自然科学基金;

关键词：

imidazo[1,2-a]pyridines; oxidative C-H/C-H coupling; fluorophores; regioselectivity; palladium; PART; 2; FLUORESCENT; POTENT; LIGANDS; DESIGN; DISCOVERY; ACCESS; CONSTRUCTION; HETEROCYCLES; BIHETEROARYL;

D O I：

10.1055/s-0040-1706000

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A rapid access to a series of N-heteroarene fluorophores has been developed on the basis of the palladium-catalyzed direct oxidative C-H/C-H coupling of imidazo[1,2-a]pyridines with thiophenes/furans. The photophysical properties-structure relationship was systematically investigated. The resulting N-heteroarene fluorophores present colortunable emissions (lambda(em): 431-507 nm in CH2Cl2) and high fluorescence quantum yields (up to 91% in CH2Cl2).

引用

页码：1619 / 1628

页数：10

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