Surgical treatment of acute infectious purpura fulminans in neonates

被引:0
|
作者
Parisi, Paola [1 ]
Ribuffo, Diego [1 ]
机构
[1] Sapienza Univ Rome, Dept Surg P Valdoni, Unit Plast & Reconstruct Surg, Policlin Umberto 1, Viale Policlin 155, I-00161 Rome, Italy
关键词
Skin necrosis; purpura fulminans; pediatric reconstructive surgery; skin grafting; dermal substitute; tissue engineering; VACUUM-ASSISTED CLOSURE; NEGATIVE-PRESSURE THERAPY; MENINGOCOCCAL SEPTICEMIA COMPLICATIONS; CULTURED AUTOLOGOUS KERATINOCYTES; PROTEIN-C DEFICIENCY; ARTIFICIAL SKIN; ENGINEERED SKIN; MANAGEMENT; WOUNDS; GANGRENE;
D O I
10.7363/110215
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Skin and soft tissue necrosis rarely occurs in neonates, although pediatric and plastic surgery services should be aware of this urgent condition [1]. Plastic surgeons are frequently consulted regarding management of soft tissue or open wounds to perform debridement, plan reconstruction or proceed with amputation. Several situations may lead to this condition. Predisposing factors include prematurity, hypercoagulability state, umbilical artery cannulation, thrombosis, hyperosmolar fluid infusions, sepsis [1], thermal abnormality, dry labor and purpura fulminans (PF) [2, 3]. Additional cases have been described as a consequence of intrauterine compression [4], as well as in newborns of diabetic mothers, who have a higher tendency to develop intravascular coagulation [5]. © 2022. Journal of Pediatric and Neonatal Individualized Medicine. All Rights Reserved.
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页数:7
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