共 21 条
Terahertz Spectroscopic Diagnosis and Sub-wavelength Imaging of Myelin Deficit Monkey Brain with Chemometric Techniques
被引:0
|作者:
Zhu, Li-Guo
[1
,2
]
Zou, Yi
[1
]
Li, Jiang
[1
,2
]
Cui, Yiyuan
[3
]
Du, Liang-Hui
[1
,2
]
Chen, Mina
[3
]
Zhao, Jianheng
[1
]
机构:
[1] China Acad Engn Phys, Inst Fluid Phys, Interdisciplinary Lab Phys & Biomed, Mianyang 621900, Sichuan, Peoples R China
[2] China Acad Engn Phys, Microsyst & Terahertz Res Ctr, Mianyang 621900, Sichuan, Peoples R China
[3] Sichuan Univ, West China Hosp, State Key Lab Biotherapy, Chengdu 610041, Peoples R China
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暂无
中图分类号:
TM [电工技术];
TN [电子技术、通信技术];
学科分类号:
0808 ;
0809 ;
摘要:
Myelin Deficit of the central nervous system leads to several severe diseases in human, but lack definitive diagnostic test. In this work, we proposed and performed terahertz spectroscopy and sub -wavelength imaging combined with chemometric techniques to discriminate and evaluate the severity of myelin deficit in and rhesus monkey brains. We demonstrated THz imaging with sub-100 tm spatial resolution of brain tissues. And our spectroscopy results well match with pathological analysis, indicating that THz is a quick, powerful, evolving tool for identification and evaluation in preclinical animals and potentially in para-clinical biopsy of humans.
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