Pathogenesis of liver involvement during dengue viral infections

被引:184
|
作者
Seneviratne, S. L.
Malavige, G. N.
de Silva, H. J.
机构
[1] John Radcliffe Hosp, Dept Clin Immunol, Oxford OX3 9DU, England
[2] Univ Jayawardenapura, Fac Med, Dept Microbiol, Nugegoda, Sri Lanka
[3] Univ Kelaniya, Fac Med, Dept Med, Kelaniya, Sri Lanka
关键词
dengue; liver; transaminases; immune mechanisms; clinical observations;
D O I
10.1016/j.trstmh.2005.10.007
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The dengue virus can infect many cell types and cause diverse clinical and pathological effects. We describe clinical and experimental observations that suggest that liver involvement occurs during dengue infections, and we outline the possible rote played by host immune responses in this process. (C) 2005 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:608 / 614
页数:7
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