Inhibition of aflatoxin biosynthesis by phenolic compounds

被引：45

作者：

Hua, SST ^{[1
]}

Grosjean, OK ^{[1
]}

Baker, JL ^{[1
]}

机构：

[1] ARS, USDA, Western Reg Res Ctr, Albany, CA 94710 USA

来源：

LETTERS IN APPLIED MICROBIOLOGY | 1999年 / 29卷 / 05期

关键词：

D O I：

10.1046/j.1472-765X.1999.00635.x

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The phenolic compounds acetosyringone, syringaldehyde and sinapinic acid inhibited the biosynthesis of aflatoxin B-1 (AFB(1)) by A. flavus. Acetosyringone was the most active among the three compounds, inhibiting aflatoxin level by 82% at 2 m mol l(-1). The synthesis and accumulation of norsolorinic acid, an aflatoxin biosynthetic intermediate, was also inhibited. These results suggest that at least one step early in the AFB(1) biosynthetic pathway is inhibited by the phenolics.

引用

页码：289 / 291

页数：3

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