PARIS: A phase I study of pembrolizumab anti-PD-1 monoclonal antibody in combination with radiotherapy (RT) in locally advanced non-small cell lung cancer (NSCLC)

被引：0
|
作者：
Kordbacheh, T. [1 ,2 ]
Chan, C. [1 ]
Bossons, A. [2 ,3 ]
Franks, K. [4 ]
McDonald, F. [5 ]
Forster, M. [6 ]
Mendes, R. [7 ]
Quezada, S. [8 ]
Dovedi, S. [9 ]
Ralph, C. [10 ]
Popat, S. [11 ]
Harrington, K. [12 ,13 ]
Melcher, A. [14 ]
Popple, A. [9 ]
Illidge, T. [9 ]
Faivre-Finn, C. [1 ,2 ]
机构：
[1] Christie NHS Fdn Trust, Clin Oncol, Manchester, Lancs, England
[2] Univ Manchester, Manchester, Lancs, England
[3] Christie NHS Fdn Trust, Clin Trials Unit, Manchester, Lancs, England
[4] St James Univ Hosp, Leeds Canc Ctr, Clin Oncol, Leeds, W Yorkshire, England
[5] Royal Marsden NHS Fdn Trust, Clin Oncol, London, England
[6] UCL, Oncol, London, England
[7] Univ Coll London Hosp, Clin Oncol, London, England
[8] UCL Canc Inst, Immune Regulat & Tumour Immunotherapy, London, England
[9] Canc Res UK Manchester Inst, Targeted Therapy, Manchester, Lancs, England
[10] Univ Leeds, Leeds Immunotherapy Team, Leeds, W Yorkshire, England
[11] Royal Marsden Hosp, Lung Oncol Unit, London, England
[12] Royal Marsden NHS Fdn Trust, Clin Oncol, Targeted Therapy, Manchester, Lancs, England
[13] Inst Canc Res, Manchester, Lancs, England
[14] Inst Canc Res, Translat Immunol, Manchester, Lancs, England
来源：
LUNG CANCER | 2017年 / 103卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
164
引用
收藏
页码：S75 / S76
页数：2
相关论文
共 50 条
  • [11] Concomitant radiotherapy (RT) with docetaxel for unresectable locally advanced non-small cell lung cancer (LA-NSCLC)
    Fuente, N.
    Mane, J. M.
    Rubio, I.
    Carrera, S.
    Martinez-Bueno, A.
    Lopez de Argumedo, G.
    Ferreiro, J.
    Abon, G.
    Garrido, P.
    Lopez-Vivanco, G.
    JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (15)
  • [12] PHASE I STUDY OF ANTI-PD-1 ANTIBODY ONO-4538 AND CHEMOTHERAPY IN PATIENTS WITH ADVANCED NON-SMALL-CELL LUNG CANCER
    Kanda, Shintaro
    Tanaka, Ayako
    Utsumi, Hirofumi
    Sunami, Kuniko
    Mizugaki, Hidenori
    Horinouchi, Hidehito
    Fujiwara, Yutaka
    Nokihara, Hiroshi
    Yamamoto, Noboru
    Tamura, Tomohide
    ANNALS OF ONCOLOGY, 2014, 25
  • [13] Retreatment With Anti-PD-L1 Antibody in Advanced Non-small Cell Lung Cancer Previously Treated With Anti-PD-1 Antibodies
    Fujita, Kohei
    Uchida, Naohiro
    Yamamoto, Yuki
    Kanai, Osamu
    Okamura, Misato
    Nakatani, Koichi
    Sawai, Satoru
    Mio, Tadashi
    ANTICANCER RESEARCH, 2019, 39 (07) : 3917 - 3921
  • [14] Incidence and Grade of Pneumonitis in Advanced Non-Small Cell Lung Cancer (NSCLC) Patients Treated with Anti-PD-1 Antibodies
    Yam, Andrew
    Barnet, Megan
    Mersiades, Anthony
    Gao, Bo
    Kao, Steven
    Boyer, Michael
    Hui, Rina
    Nagrial, Adnan
    JOURNAL OF THORACIC ONCOLOGY, 2017, 12 (01) : S1308 - S1308
  • [15] Palliative thoracic radiotherapy in locally advanced/metastatic non-small cell lung cancer (NSCLC)
    Maclennan, K.
    Campbell, S.
    Little, F.
    Erridge, S.
    Evans, T.
    Price, A.
    LUNG CANCER, 2016, 91 : S53 - S54
  • [16] Radiotherapy with carbogen breathing and nicotinamide in locally advanced non-small cell lung cancer (NSCLC)
    Yavuz, AA
    Atahan, IL
    Akyol, FH
    Yavuz, M
    Zorlu, AF
    EUROPEAN JOURNAL OF CANCER, 1997, 33 : 447 - 447
  • [17] Phase I Study of Pembrolizumab (MK-3475; Anti-PD-1 Monoclonal Antibody) in Patients with Advanced Solid Tumors
    Patnaik, Amita
    Kang, S. Peter
    Rasco, Drew
    Papadopoulos, Kyriakos P.
    Elassaiss-Schaap, Jeroen
    Beeram, Muralidhar
    Drengler, Ronald
    Chen, Cong
    Smith, Lon
    Espino, Guillermo
    Gergich, Kevin
    Delgado, Liliana
    Daud, Adil
    Lindia, Jill A.
    Li, Xiaoyun Nicole
    Pierce, Robert H.
    Yearley, Jennifer H.
    Wu, Dianna
    Laterza, Omar
    Lehnert, Manfred
    Iannone, Robert
    Tolcher, Anthony W.
    CLINICAL CANCER RESEARCH, 2015, 21 (19) : 4286 - 4293
  • [18] MK-3475 (ANTI-PD-1 MONOCLONAL ANTIBODY) FOR NON-SMALL CELL LUNG CANCER (NSCLC): ANTITUMOR ACTIVITY AND ASSOCIATION WITH TUMOR PD-L1 EXPRESSION
    Gandhi, Leena
    Lubiniecki, Gregory
    Balmanoukian, Ani
    Hui, Rina
    Hamid, Omid
    Rizvi, Naiyer A.
    Leighl, Natasha
    Gubens, Matthew
    Goldman, Jonathan W.
    Emancipator, Kenneth
    Dolled-Filhart, Marisa
    Lunceford, Jared K.
    Niewood, Michelle
    Gergich, Kevin
    Garon, Edward B.
    JOURNAL OF THORACIC ONCOLOGY, 2014, 9 (09) : S154 - S154
  • [19] N0321: A phase II study of bortezomib, paclitaxel, carboplatin (CBCDA), and radiotherapy (RT) for locally advanced non-small cell lung cancer (NSCLC)
    Schild, Steven E.
    Foster, Nathan R.
    Molina, Julian R.
    Dy, Grace K.
    Rowland, Kendrith M.
    Sarkaria, Jann Nagina
    Thomas, Sachdev P.
    Northfelt, Donald W.
    Kugler, John William
    Adjei, Alex A.
    JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (15)
  • [20] MK-3475 (anti-PD-1 monoclonal antibody) for non-small cell lung cancer (NSCLC): Antitumor activity and association with tumor PD-L1 expression
    Gandhi, Leena
    Balmanoukian, Ani
    Hui, Rina
    Hamid, Omid
    Rizvi, Naiyer A.
    Leighl, Natasha
    Gubens, Matthew
    Goldman, Jonathan W.
    Lubiniecki, Gregory M.
    Emancipator, Kenneth
    Dolled-Filhart, Marisa
    Lunceford, Jared K.
    Niewood, Michelle
    Gergich, Kevin
    Garon, Edward B.
    CANCER RESEARCH, 2014, 74 (19)
12345