High clinical efficacy in poor prognosis patients with metastatic melanoma treated with an IDO/PD-L1 peptide vaccine in combination with nivolumab

被引：0
|
作者：
Kjeldsen, Julie W. [1 ]
Lorentzen, Cathrine L. [1 ]
Martinenaite, Evelina [1 ,2 ]
Ellebaek, Eva [1 ]
Donia, Marco [1 ]
Ehrnrooth, Eva [3 ]
Andersen, Mads H. [1 ,2 ]
Svane, Inge Marie [1 ]
机构：
[1] Herlev Hosp, Dept Oncol, Natl Ctr Canc Immune Therapy CCIT DK, Herlev, Denmark
[2] Herlev Hosp, Dept Oncol, IO Biotech ApS, Herlev, Denmark
[3] IO Biotech ApS, Copenhagen, Denmark
来源：
CANCER RESEARCH | 2022年 / 82卷 / 12期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
CT535
引用
收藏
页数：2
相关论文
共 50 条
  • [21] Loss of PD-L1 expression in metastatic Merkel cell carcinoma strongly correlates with a poor prognosis
    Nakamura, M.
    Teramoto, Y.
    Yasuda, M.
    Wada, H.
    Ozawa, T.
    Umemori, Y.
    Ogata, D.
    Kobayashi, T.
    Hata, M.
    Morita, A.
    [J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2019, 139 (05) : S23 - S23
  • [22] PD-L1 Testing and Clinical Benefit in Patients Treated with CPI
    Kovacevic, M.
    Ivanovic, M.
    Kern, I.
    Cufer, T.
    [J]. JOURNAL OF THORACIC ONCOLOGY, 2019, 14 (10) : S781 - S782
  • [23] PD-L1 expression and outcome of advanced melanoma patients treated with anti-PD-1/PD-L1 agents: a meta-analysis
    Abdel-Rahman, Omar
    [J]. IMMUNOTHERAPY, 2016, 8 (09) : 1081 - 1090
  • [24] Comparison between four PD-L1 IHC assays and association with efficacy of Nivolumab in previously treated NSCLC patients regular
    Sato, Yuki
    Fujimoto, Daichi
    Uehara, Keiichiro
    Imaoka, Yuki
    Hayashi, Kentaro
    Ishida, Kaori
    Fukuoka, Junya
    Imai, Yukihiro
    Tomii, Keisuke
    [J]. ANNALS OF ONCOLOGY, 2017, 28
  • [25] A multicenter, randomized, double-blind phase III study of HBI-8000 combined with nivolumab versus placebo with nivolumab in patients with unresectable or metastatic melanoma not previously treated with PD-1 or PD-L1 inhibitors
    Khushalani, N. I.
    Shue, H.
    Gedye, C.
    Mazumder, A.
    Sharma, S.
    Eastgate, M.
    Majem Tarruella, M.
    Antonanzas Basa, M.
    Montaudie, H.
    Marais-Nieman, R.
    de la Cruz Merino, L.
    Clements, A.
    Mortier, L.
    Jameson, M.
    Shojaei, F.
    Ning, J.
    Aiyer, L.
    Gillings, M.
    Kabbinavar, F.
    Ascierto, P.
    [J]. ANNALS OF ONCOLOGY, 2022, 33 : S1444 - S1444
  • [26] Elevated baseline serum PD-1 or PD-L1 predicts poor outcome of PD-1 inhibition therapy in metastatic melanoma
    Ugurel, S.
    Schadendorf, D.
    Horny, K.
    Sucker, A.
    Schramm, S.
    Utikal, J.
    Pfoehler, C.
    Herbst, R.
    Schilling, B.
    Blank, C.
    Becker, J. C.
    Paschen, A.
    Zimmer, L.
    Livingstone, E.
    Horn, P. A.
    Rebmann, V
    [J]. ANNALS OF ONCOLOGY, 2020, 31 (01) : 144 - 152
  • [27] THE ASSOCIATION OF SOLUBLE PD-L1 AND TREATMENT RESPONSE TO NIVOLUMAB IN PATIENTS WITH METASTATIC RENAL CELL CARCINOMA
    Wakita, Naoto
    Bando, Yukari
    Furukawa, Junya
    Hinata, Nobuyuki
    Nakano, Yuzo
    Fujisawa, Masato
    [J]. JOURNAL OF UROLOGY, 2023, 209 : E372 - E372
  • [28] PD-L1 EXPRESSION AND EFFICACY IN PATIENTS TREATED WITH PEMBROLIZUMAB VS IPILIMUMAB FOR ADVANCED MELANOMA IN KEYNOTE-006
    Carlino, M.
    Emancipator, K.
    Ibrahim, N.
    Zhou, H.
    Schadendorf, D.
    Ribas, A.
    Gonzalez, R.
    Hoeller, C.
    Bar-Sela, G.
    Barrow, C.
    Chao, D.
    Wolter, P.
    Berking, C.
    Straume, O.
    Berrocal, A.
    Holgado, E.
    Gangadhar, T. C.
    Weiss, G.
    [J]. ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 2016, 12 : 44 - 44
  • [29] Clinical efficacy and correlation with tumor PD-L1 expression in patients (pts) with melanoma (MEL) treated with the anti-PD-1 monoclonal antibody MK-3475
    Kefford, Richard
    Ribas, Antoni
    Hamid, Omid
    Robert, Caroline
    Daud, Adil
    Wolchok, Jedd D.
    Joshua, Anthony M.
    Hodi, F. Stephen
    Gangedher, Tara C.
    Hersey, Peter
    Weber, Jeffrey S.
    Dronca, Roxana Stefanie
    Patnaik, Amite
    Zarour, Hassans M.
    Dolled-Filhart, Marisa
    Lunceford, Jared
    Emancipator, Kenneth
    Ebbinghaus, Scot
    Rang, Soonmo Peter
    Hwu, Wen-Jen
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (15)
  • [30] A PD-1/PD-L1 Proximity Assay as a Theranostic Marker for PD-1 Blockade in Patients with Metastatic Melanoma
    Girault, Isabelle
    Adam, Julien
    Shen, Shensi
    Roy, Severine
    Brard, Caroline
    Faouzi, Sara
    Routier, Emilie
    Lupu, Jeremy
    Warren, Sarah
    Sorg, Kristina
    Ong, SuFey
    Morel, Pascale
    Scoazec, Jean-Yves
    Vagner, Stephan
    Robert, Caroline
    [J]. CLINICAL CANCER RESEARCH, 2022, 28 (03) : 518 - 525
12345