Airway eicosanoids in acute severe respiratory syncytial virus bronchiolitis

被引：36
|
作者：
Sznajer, Y
Westcott, JY
Wenzel, SE
Mazer, B
Tucci, M
Toledano, BJ
机构：
[1] Univ Montreal, Hop St Justine, Pediat Intens Care Unit, Montreal, PQ H3T 1C5, Canada
[2] McGill Univ, Meakins Christie Lab, Montreal, PQ, Canada
[3] Natl Jewish Med & Res Ctr, Dept Med, Denver, CO USA
来源：
JOURNAL OF PEDIATRICS | 2004年 / 145卷 / 01期
关键词：
D O I：
10.1016/j.jpeds.2004.03.049
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
We prospectively studied the levels of eicosanoids in intubated patients with severe bronchiolitis and compared them to electively intubated non-infected infants. LeukotrieneE(4)(LTE4), leukotrieneB(4) (LTB4), and prostaglandinE(2) (PGE(2)) levels were significantly increased (P < .01) from endotracheal (ET) aspirates of infants with bronchiolitis compared with controls, as were urinary LTE4 levels (P < .001). We conclude that eicosanoids are increased in the tracheal aspirates and urine of children with bronchiolitis.
引用
收藏
页码：115 / 118
页数：4
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