Synthesis of annulated γ-carbolines by palladium-catalyzed intramolecular iminoannulation

被引：34
|
作者：
Zhang, HM [1 ]
Larock, RC [1 ]
机构：
[1] Iowa State Univ, Dept Chem, Ames, IA 50011 USA
来源：
ORGANIC LETTERS | 2002年 / 4卷 / 18期
关键词：
D O I：
10.1021/ol026255u
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[GRAPHICS] A variety of N-substituted 2-bromo-1H-indole-3-carboxaldehydes incorporating an alkyne-containing tether on the indole nitrogen have been converted to the corresponding tert-butylimines, which have been subjected to palladium-catalyzed intramolecular iminoannulation, affording various annulated gamma-carbolines in excellent yields.
引用
收藏
页码：3035 / 3038
页数：4
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